Microneedling Versus Carboxytherapy in Stria Distensae Rubra

N/AActive Not RecruitingNCT07001644

Alexandria University50 enrolled

Overview

The aim of this study is to evaluate and compare the efficacy and safety of microneedling and carboxytherapy either with or without platelet-rich plasma in the treatment of striae distensae rubra.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Striae Distensae

Interventions

microneedlingDEVICE

microneedling with topical application of PRP on one side of abdomen and microneedling only on the other side.

CarboxytherapyDEVICE

carboxytherapy with intradermal injection of PRP on one side of abdomen and carboxytherapy only on the other side.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Female patients. * Age ranging from 18-45 years old. * Fitzpatrick skin type III-IV. * Striae distensae rubra on the abdomen (bilateral and more or less symmetrical). Exclusion Criteria: * Patients taking immunosuppressants or having any disease affecting wound healing including diabetes. * Patients receiving systemic glucocorticoids for chronic health conditions. * Patients with chronic dermatologic diseases such as psoriasis and vitiligo. * Pregnant and lactating females. * Patients with a tendency for keloid formation. * Patients with endocrine disturbance. * Patients with autoimmune diseases, systemic diseases such as severe anemia, respiratory, cardiac, renal or liver disorder. * Patients with bleeding and coagulation disorders. * Patients who received any form of treatment for their SD in the past 6 months.

Locations (1)

Alexandria Faculty of Medicine

Alexandria, Egypt

Outcomes

Primary Outcomes

Reduction in the size of the stria distensae rubra

will be assessed by digital photography, actual measurement of the stria before and after treatment, and objective assessment of the percent of improvement

Time frame: group I: six sessions over 18 weeks , group II: 6 sessions over 12 weeks, followed in both groups by three months of follow up

Data from ClinicalTrials.gov

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