The Effect of Honey-sweetened Coffee, Black Tea and Green Tea on Some Physiological Parameters

University of Uyo Teaching Hospital70 enrolled

Overview

The goal of this clinical trial is to investigate whether a three-day consumption of honey-sweetened black tea, green tea, and coffee will have an effect on blood pressure, heart rate, and blood glucose. The main questions it aims to answer are: Does honey-sweetened black tea, green tea, and coffee, respectively, have the ability to influence blood pressure, heart rate, or blood glucose level? Research will compare honey-sweetened black tea, green tea, and coffee to a placebo (warm water) to see if honey-sweetened black tea, green tea, and coffee work to reduce or increase blood pressure, heart rate, or blood glucose. Participants will: Take honey-sweetened black tea, green tea, and coffee, OR plain black tea, green tea, and coffee, OR warm water, one cup a day for 3 days The beverages will be taken at the Physiology laboratory, University of Uyo, and the participants will be observed for 60 minutes, during which their blood pressure, heart rate, and blood glucose level will be measured. This procedure will be repeated for the 3 days of study.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Blood Pressure Heart Rate Blood Glucose

Interventions

Warm water at 35 oCOTHER

The placebo for the control group

CoffeeOTHER

Instant coffee, Nescafé Gold Blend, manufactured by Nestlé Coffee Brand, Nestlé Global

Honey-sweetened coffeeOTHER

Instant coffee plus raw dark amber honey produced by Apis mellifera adansonii

Green teaOTHER

Qualitea Natural Green Tea, packed by Qualitea Ceylon (PVT) LTD

Honey-sweetened green teaOTHER

Green tea plus honey

Black teaOTHER

Lipton Yellow Label Black Tea

Honey-sweetened black teaOTHER

Black tea plus honey

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 26 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Inclusion criteria are as follows: * Age between 18 and 26 * Non-habitual coffee and tea drinkers who consume coffee, green tea, or black tea 2-5 times in the last two months * Non-allergic to coffee, green tea, black tea, or honey * Absence of medication use * Will refrain from ingesting energy drinks, carbonated beverages, caffeinated beverages, or food for 24 hours before the study and throughout the study periods * Will not consume anything except water after 11 p.m. during the experimental days Will be available and cooperate throughout the study duration. Exclusion Criteria: Exclusion criteria are as follows: * Presence of cardiovascular disorders, hypertension, or diabetes * Blood pressure above 120/80 mmHg and random blood glucose above 125 mg/dL * Alcohol intake * Smoking * Habitual coffee or tea drinker

Outcomes

Primary Outcomes

Blood pressure

Time frame: Will be measured before consumption of the beverages and at 15, 30, 45, and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.

Heart rate

Time frame: Will be measured before consumption of the beverages and at 15, 30, 45, and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.

Blood glucose

Time frame: Will be measured before consumption of the beverages and at 30 and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.

Secondary Outcomes

Age

Time frame: Will obtained during the eligibility process

Height

Time frame: Will be measured on the first day of the experiment before the commencement of the experiment.

Body weight

Time frame: Measurements will be taken over the course of the 3-day study prior to the commencement of the experiment each day.