Efficacy of Notrande Shuhuajun Probiotic Supplement on Lmproving Constipation in Preschool Children

Inclusion Criteria: * Participants must be preschool children (aged 3-6); * Participants were diagnosed with functional constipation based on Rome IV criteria; * Participants agreed not to take any drugs, supplements, or other dairy products during the trial period; * Participants agreed not to take any other prebiotic/bacterial drugs, supplements, or dairy products including yogurt beverages during the trial period; * Be willing to refrain from participating in other interventional clinical studies during the trial period; * Be able to fully understand the nature, purpose, benefits obtained, as well as possible risks and side effects of this study; * Be willing to comply with all test requirements and procedures; * Sign the informed consent form; Exclusion Criteria: * In the treatment of gastrointestinal symptoms; * Lactose intolerance; * Currently suffering from other organic diseases that affect intestinal function, such as a history of gastrointestinal resection, colon or rectal cancer, inflammatory bowel disease, diabetes, hyperthyroidism or hypothyroidism, congenital megacolon, scleroderma, anorexia nervosa, etc; * Have been controlling diet, increasing exercise, or taking drugs to control weight or affect appetite in the last three months; * Have any of the following medical histories or have been clinically diagnosed with any of the following diseases that may affect the evaluation of the trial effect: obvious gastrointestinal dysfunction, liver, kidney, endocrine, blood, respiratory and cardiovascular diseases; * Current or past abuse of alcohol or other prohibited drugs, supplements or OTC prescription drugs may cause intestinal dysfunction or affect the evaluation of the test results; * According to the researchers' judgment, drugs that may affect gastrointestinal function or the immune system are currently being frequently used; * Laxatives or other digestive AIDS were used two weeks before the start of the trial; * Have consumed dairy products or other foods containing prebiotics/bacteria 10 days before the start of the trial; * The research doctors believed that the volunteers could not fully cooperate with the trial arrangements;