Bright light therapy has been shown to be effective for the treatment of both seasonal and non-seasonal unipolar depression as well as bipolar depression, primarily in outpatients under the age of 60. There is a dearth of studies exploring the efficacy of this treatment modality among elderly depressed inpatients, which is our study population.
Investigators are studying the ability of light therapy to reduce depressive symptoms in elderly patients who are hospitalized with unipolar depression (depression that is not due to bipolar disorder). Participants will receive either active light treatment or inactive treatment (also known as placebo).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
20
the Verilux® HappyLight® Lumi Plus light therapy box, which delivers UV-free, full-spectrum LED light at an intensity of 10,000 lux
The control group will use the same light box device, configured to emit dim red light. This will be achieved by setting the box to its lowest brightness setting and overlaying a translucent red filter over the light display. This setup is intended to maintain the appearance and experience of light exposure while minimizing any therapeutic effect.
Medical University of South Carolina Institute of Psychiatry Senior Care Unit
Charleston, South Carolina, United States
Study completion rate
Percentage of patients who complete the study while psychiatrically hospitalized
Time frame: Up to week 6 (Upon time of discharge from inpatient unit)
Adequacy of allocation blinding
assessed by the proportion of participants who correctly identify their study arm allocation. Blinding will be considered adequate if the proportion of correct guesses does not significantly exceed chance levels
Time frame: Up to week 6 (Upon time of discharge from inpatient unit)
Preliminary efficacy data - Mean change in Hamilton Depression Rating Scale 17 item scale (HAMD-17)
HAMD-17 is a commonly used clinician rating scale for depressive symptoms
Time frame: Day of enrollment, week 1, week 2, week 4, week 6
Preliminary efficacy data - Mean change in Beck Depression Inventory II (BDI-II) Score
BDI-II is a commonly used self-report rating scale for depressive symptoms
Time frame: Day of enrollment, week 1, week 2, week 4, week 6
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