Clinical Efficacy Trial of Burdock Root Extract in Patients With Asymptomatic Hyperuricaemia

Inclusion Criteria: * Hyperuricaemia confirmed by a laboratory, uric acid level from 360 to 540 μmol/L in women and from 420 to 540 μmol/L in men; * Age from 35 to 65 years at the baseline; * Patients examined by an experienced specialist not revealing any clinical evidences of gout or other somatic consequences of hyperuricaemia; * Not taking any other nutritional additives; * Women of reproductive age having negative pregnancy test at the baseline and at the end of the trial; * Not taking any diuretics, or their administration based on a regimen usual for a patient, without changes; * Not taking part in any other clinical trials; * Consent and voluntarily signed informed consent form for participation in the clinical trial. Exclusion Criteria: * Age \<35 or \>65 years; * Fever (above 36.8 оС); * Pregnancy and lactation; * Patients with any somatic evidences of hyperuricaemia including gout taking antigout drugs during or within 6 months before the trial; * Patients with mental disorders / taking antipsychotics or antidepressants; * Patients not giving (informed) consent to participate in the trial; * Patients causing doubts of the study doctor as to their motivation to comply with the trial; * Presence of any concomitant decompensated diseases or acute conditions able to influence results of the trial; * Alcohol abuse and drug addiction; * Changes in taking diuretics within a month before and during the trial; * Participation in any other clinical trial; * Taking any nutritional additives.