Neutrophil-to Lymphocyte and Monocyte-to-Lymphocyte Ratios in Exudative Pleural Effusion

Alexandria University60 enrolled

Overview

Exudative pleural effusion (EPE) presents a diagnostic challenge, requiring accurate biomarkers to predict outcomes and guide treatment. The neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) in pleural fluid are emerging as potential prognostic markers. We aimed to assess the diagnostic and prognostic utility of pleural fluid NLR and MLR in EPE.

Pleural fluid NLR and MLR are reliable biomarkers for diagnosing malignant pleural effusion and predicting poorer survival outcomes. These ratios may be useful in clinical practice, especially in resource-limited settings, to guide decision-making in the management of pleural effusions.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Effusion

Interventions

medical thoracoscopyPROCEDURE

pleural fluid aspiration and cellular analysis

Eligibility

Sex: ALLMin age: 18 Months

Medical Language ↔ Plain English

Inclusion Criteria: * adult patients aged 18-80 years with an EPE diagnosis confirmed by thoracentesis. Exclusion Criteria: * Exclusion criteria included patients with a history of recent surgery, corticosteroid use, or those with mixed effusion types.

Locations (1)

Chest Department -Faculty of Medicine

Alexandria, Egypt, Egypt

Outcomes

Primary Outcomes

MLR and NLR measuring in pleural fluid

counting pleural fluid monocytes,lymphocytes and neutrophils

Time frame: 1 month

Data from ClinicalTrials.gov

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