The goal of this clinical trial is to to assess the efficacy AlphaWave® L-Theanine on mental acuity/cognitive function and stress relief in healthy adults with moderate stress. The main question it aims to answer is: Is there a difference in change in mental acuity from pre- to post-dose between AlphaWave® L-Theanine and placebo? Participants will asked to provided a single dose of one capsule of a single dose of one capsule of AlphaWave® L-Theanine or one placebo capsule with 250 ml of room temperature water, and asked to complete tasks to assess cognitive function.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
40
Study staff will provide participants with a single dose of one capsule of AlphaWave® L-Theanine or one placebo capsule with 250 ml of room temperature water.
Study staff will provide participants with a single dose of one capsule of AlphaWave® L-Theanine or one placebo capsule with 250 ml of room temperature water.
KGK Science Inc.
London, Ontario, Canada
RECRUITINGThe difference in change in mental acuity from pre- to post-dose between AlphaWave® L-Theanine and placebo
The difference in change in mental acuity from pre- to post-dose between AlphaWave® L-Theanine and placebo as assessed by reaction time using the Computerized Mental Performance Assessment System (COMPASS) tasks.
Time frame: 1 hour pre-dose and 1 hour post-dose
The difference in change in Cognitive Demand Battery (CDB) from pre- to post-dose between AlphaWave® L-Theanine and placebo
The difference in change in Cognitive Demand Battery (CDB) from pre- to post-dose between AlphaWave® L-Theanine and placebo as assessed by COMPASS.
Time frame: 1 hour pre-dose and 1 hour post-dose
The difference in change in attention from pre- to post-dose between AlphaWave® L-Theanine and placebo
The difference in change in attention from pre- to post-dose between AlphaWave® L-Theanine and placebo as assessed by COMPASS.
Time frame: 1 hour pre-dose and 1 hour post-dose
The difference in change in episodic, working and spatial memory from pre- to post-dose between AlphaWave® L-Theanine and placebo
The difference in change in episodic, working and spatial memory from pre- to post-dose between AlphaWave® L-Theanine and placebo as assessed by COMPASS.
Time frame: 1 hour pre-dose and 1 hour post-dose
The difference in change in psychomotor, processing, and motor speed from pre- to post-dose between AlphaWave® L-Theanine and placebo
The difference in change in psychomotor, processing, and motor speed from pre- to post-dose between AlphaWave® L-Theanine and placebo as assessed by COMPASS.
Time frame: 1 hour pre-dose and 1 hour post-dose
The difference in change in sustained attention from pre- to post-dose between AlphaWave® L-Theanine and placebo
The difference in change in sustained attention speed from pre- to post-dose between AlphaWave® L-Theanine and placebo as assessed by the Go/No Go assessment.
Time frame: 1 hour pre-dose and 1 hour post-dose
The difference in change in stress from pre- to post-dose between AlphaWave® L-Theanine and placebo
The difference in change in stress from pre- to post-dose between AlphaWave® L-Theanine and placebo as assessed by the Perceived Stress Scale (PSS). A scale of 1 to 10, with 10 indicating more perceived stress.
Time frame: 1 hour pre-dose and 1 hour post-dose
The difference in change in stress from pre- to post-dose between AlphaWave® L-Theanine and placebo
The difference in change in stress from pre- to post-dose between AlphaWave® L-Theanine and placebo as assessed by salivary cortisol.
Time frame: 1 hour pre-dose and 1 hour post-dose
The difference in change in heart rate from pre- to post-dose between AlphaWave® L-Theanine and placebo
The difference in change in heart rate from pre- to post-dose between AlphaWave® L-Theanine and placebo as assessed by salivary cortisol.
Time frame: 1 hour pre-dose and 1 hour post-dose
The difference in change in blood pressure from pre- to post-dose between AlphaWave® L-Theanine and placebo
The difference in change in blood pressure from pre- to post-dose between AlphaWave® L-Theanine and placebo as assessed by salivary cortisol.
Time frame: 1 hour pre-dose and 1 hour post-dose
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