The Silencia PD (peritoneal dialysis) cycler offers a pediatric (PAED) mode with advanced features such as Time and Volume Optimization (TAVO), supporting precise and individualized treatment. This study evaluates the efficacy and tolerability of Automated Peritoneal Dialysis (APD) using the Silencia PD cycler in patients weighing ≤ 20 kg and able to tolerate a minimum inflow volume of 100 mL. The primary objective is to determine whether patients achieve a total weekly Kt/Vurea ≥ 1.8.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
13
Patients weighing less than 20 kg will be treated for 4 weeks with APD using the PAED mode of the Silencia PD cycler
Total weekly Kt/V urea
The primary objective is to determine whether patients achieve a total weekly Kt/V urea ≥ 1.8.
Time frame: The primary endpoint is total Kt/Vurea at week 2 and 4
Mean daily ultrafiltration (UF)
Time frame: Mean UF will be measured at weeks 2 and 4
Residual renal function (RRF)
Renal urea clearance
Time frame: RRF will be measured at weeks 2 and 4
Residual renal function (RRF)
Renal creatinine clearance
Time frame: RRF will be measured at weeks 2 and 4
Residual renal function (RRF)
24h urine output
Time frame: RRF will be measured at weeks 2 and 4
Residual renal function (RRF)
GFR (calculated during the analysis)
Time frame: RRF will be measured at weeks 2 and 4
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.