The aim of this study is to determine whether a modified fasting protocol can reduce the potential risk of aspiration for patients currently prescribed GLP1-RAs.
The overall objective of this project is to identify a reasonable means by which patients on GLP1-RAs can be safely cared for in the perioperative period that can be agreed upon by all groups involved in perioperative patient care. This will be assessed in patients undergoing upper endoscopy specifically since assessment of gastric contents would be minimally invasive for this patient population receiving anesthetic care.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
PREVENTION
Masking
SINGLE
Enrollment
150
Patients will follow a full-liquid diet 48 hours prior to their procedure, clear liquid diet 24 hours prior to their procedure, and nothing by mouth (NPO) after midnight on the day of their procedure
Mayo Clinic in Rochester
Rochester, Minnesota, United States
RECRUITINGGastric contents
Number of patients who were found to have gastric contents within the stomach during the upper endoscopy.
Time frame: Baseline
Diagnosis of aspiration within 72 hours of procedure
Whether or not a patient was diagnosed with aspiration will be determined via chart review for 72 hours after the completion of upper endoscopy. A note documenting aspiration or an ICD code associated with aspiration will indicate that this outcome occurred.
Time frame: From the time of upper endoscopy until 72 hours post-procedure.
Aspiration pneumonitis diagnosis postoperatively
The number of patients who have a diagnosis of aspiration pneumonitis, as identified by the presence of ICD codes J69.0 or J69.8, postoperatively.
Time frame: 72 hours after completion of upper endoscopy
Postprocedural ICU admission
The number of patients who were admitted to the ICU immediately after upper endoscopy.
Time frame: Immediately after upper endoscopy
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