This multicenter research project aims to correlate objective testing of muscle mass, muscle strength, neuromuscular activation, walking speed and other functional tests with everyday activity and subjective quality of life after total knee arthroplasty. For this purpose, 400 patients from 5 orthopedic departments in Germany and USA will be examined at the time points pre-op, six weeks, three, six and 12 months post-op.
Study Type
OBSERVATIONAL
Enrollment
400
The main target parameters are muscle mass (sonography), muscle strength (isometric maximum strength measurement), neuromuscular activation (surface EMG), functionality (e.g. 6MWT, chair rising test), knee swelling and subjective assessment of everyday and leisure activities, quality of life (e.g. SF-36) and return to work
Technical University Munich
Munich, Bavaria, Germany
University Hospital Bonn
Bonn, North Rhine-Westphalia, Germany
Muscle Mass
Sonographically Analysis of the M. quadriceps femoris
Time frame: Pre-OP to 12 months Post-OP
Muscle Strength
Isometric maximal strength of the knee extensors
Time frame: Pre-OP to 12 Months Post-OP
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