Patients with HAE Type I or II who enroll in the study are asked to complete a patient diary when they experience an HAE attack. If icatibant is taken as the first treatment for the attack, the patient diary will ask questions over a 48 hour period after dosing to track the characteristics and severity of the attack along with the patient's level of anxiety.
Study Type
OBSERVATIONAL
Enrollment
88
Inapplicable
KalVista Investigative Site
Fairfax, Virginia, United States
Patient Global Impression of Change (PGI-C)
time to beginning of symptom relief defined as at least ''a little better'' (2 time points in a row)
Time frame: Within 12 hours of the first Icatibant dose adminstration
Patient Global Impression of Severity (PGI-S)
Time to first incidence of decrease from baseline (2 time points in a row)
Time frame: Within 12 hours of the first Icatibant dose adminstration
PGI-S: Time to Complete HAE Attack Resolution
time to HAE attack resolution, defined as ''none''
Time frame: Within 24 hours of the first Icatibant dose adminstration
Return to normal function
Time to return to normal daily activities. Date/Time or one of the following options: * Not Applicable - daily activities were not affected * not yet returned to normal activities
Time frame: At 48 hours after first Icatibant dose adminstration
General Anxiety Numeric Rating Scale (GA-NRS): Cumulative GA-NRS
Patient is asked 'How anxious do you feel right now?' 11-point numeric scale, 0-10 with 0=Not at all anxious and 10=Extremely anxious
Time frame: over 12 and 24 hours of the first icatibant administration
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