Efficacy and Safety of Photodynamic Therapy for CIN3

Peking University Third Hospital100 enrolled

Overview

To investigate the efficacy and safety of photodynamic therapy (20% 5-amino-ketovalerate 630nm red light) in the treatment of cervical intraepithelial neoplasia 3(CIN 3)in women in the real world

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

100

Conditions

Precancerous Cervical Lesion

Interventions

ALA-PDTPROCEDURE

use ALA\_PDT to treat the disease

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * CIN3, photodynamic therapy was required, * type 1 2 transformation area, colposcopy was sufficient * the lesion boundary was completely visible * The ECC did not indicate high-grade lesions Exclusion Criteria: * coexistence or suspicion of cancer; * TCT HSIL * involving glands * Porphyria patients, or suspected allergic to red and blue light. * severe medical comorbidities；

Locations (1)

Peking Unniversity Third Hospital

Beijing, China

RECRUITING

Outcomes

Primary Outcomes

Efficacy of the treatment

colposcopy and biopsy will be performed one month after the treatment. Patients will be categorised as having complete remission(CR) if biopsy confirmed LSIL. If CIN 2 was found after the first course of PDT, it would be categorised as partial remission(PR). Those with the same grade were categorised as persistent disease(PD). The proportion of CR after PDT treatment.

Time frame: 1 month after the treatment

Central Contacts

Qin Han

CONTACT

13810632686 Lmlfe_lynn@126.com

Data from ClinicalTrials.gov

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