The goal of this clinical trial is to learn if dihydroartemisinin (DHA) works to treat Androgenetic Alopecia (AGA) in female adults. The main question it aims to answer is: • Does DHA increase terminal hair follicles in the vertex area. Researchers will compare oral DHA plus topical minoxidil to topical minoxidil alone in female patients with AGA to see if DHA works to alleviate AGA. Participants will: * Receive oral DHA every day plus topical minoxidil or use topical minoxidil alone for 6 months. * Visit the clinic once every month for checkups and tests.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
30
DHA 20mg tid po plus daily topical minoxidil 5% for 180 days
Topical minoxidil 5% daily for 180 days
Zhongshan Hospital Fudan University
Shanghai, Shanghai Municipality, China
RECRUITINGImprovement in terminal hair follicles in the vertex area
Terminal hair follicles in the vertex area will be quantified before and at the end of treatment
Time frame: Baseline and 180-day of treatment
Change of terminal hair follicle density in the vertex area from baseline to the end of treatment
Time frame: Baseline and 180-day of treatment
Change of hair density in the vertex area from baseline to the end of treatment
Time frame: Baseline and 180-day of treatment
Change of terminal hair follicle density in the frontal area from baseline to the end of treatment
Terminal hair follicle density in the frontal area
Time frame: Baseline and 180-day of treatment
Change of hair density in the frontal area from baseline to the end of treatment
Time frame: Baseline and 180-day of treatment
Change of serum total testosterone from baseline to the end of treatment
Time frame: Baseline and 180-day of treatment
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