The study was designed to evaluate the pharmacokinetic effects of Rifampicin on HRS-5041 after oral administration of HRS-5041 tablets in healthy subjects.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
16
HRS-5041 tablets.
Rifampicin capsule.
The First Affiliated Hospital of Shandong First Medical University (Shandong Provincial Qianfoshan Hospital)
Jinan, Shandong, China
Area Under the Curve from time 0 to time t (AUC0-t)
Time frame: 0 to anticipated 23 days.
Area Under the Curve from time 0 to infinity (AUC0-∞)
Time frame: 0 to anticipated 23 days.
Maximum concentration (Cmax)
Time frame: 0 to anticipated 23 days.
Time to reach maximum concentration (Tmax)
Time frame: 0 to anticipated 23 days.
Half-life (t1/2)
Time frame: 0 to anticipated 23 days.
Apparent clearance (CL/F)
Time frame: 0 to anticipated 23 days.
Adverse events (AEs)
Time frame: 0 to anticipated 31 days.
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