Characterization and Analysis of Evoked Cortical Responses in Participants With Medication-intractable Epilepsy

University of Michigan5 enrolled

Overview

The goal of this project is to study how the brain reacts to a small electrical signal. Researchers will be using a novel combination of recording electrodes. The researchers will measure the brain response from these electrodes.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Intractable Epilepsy

Interventions

stimulating probes and electrodesDEVICE

Subdural electrodes and/or ball tip probes will be used intraoperatively to provide electrical stimulation to the brain.

Eligibility

Sex: ALLMin age: 22 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with medication intractable epilepsy who are recommended to undergo brain surgery to remove a "seizure" focus * Can provide informed consent for the study and willing to participate Exclusion Criteria: * Presence of a permanent electronic implant * Any chronic medical conditions that prevent safe placement of electrodes

Locations (1)

University of Michigan

Ann Arbor, Michigan, United States

RECRUITING

Outcomes

Primary Outcomes

Characterization of time-frequency data

From recording electrodes

Time frame: During a 20 minute research phase of a clinically indicated surgery

Characterization of local field responses (LFPs)

From recording electrodes

Time frame: During a 20 minute research phase of a clinically indicated surgery

Central Contacts

Ron Ball

CONTACT

734 936-7010 rmball@umich.edu

Data from ClinicalTrials.gov

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