Patients will undergo quantitative perfusion assessment in cardiovascular magnetic resonance imaging (dual bolus or dual sequence approach) as well as invasive coronary angiography for assessment of fractional flow reserve (FFR) including assessment of coronary flow reserve (CFR) and microcirculatory resistance (IMR).
Study Type
OBSERVATIONAL
Enrollment
200
Kerckhoff Klinik
Bad Nauheim, Hesse, Germany
Quantitative Perfusion
Correlation of myocardial blood flow and perfusion reserve in CMR with invasively dervived fractional flow reserve (FFR), coronary flow reserve (CFR) and microcirculatory resistance (IMR)
Time frame: assessment of CMR and invasive data within 24hours
Dual bolus vs dual sequence
Compare both CMR-derived quantitative perfusion for prediction of FFR/CFR/IMR
Time frame: assessment of CMR and invasive data within 24hours
Strain
Correlation of segmental perfusion and myocardial strain
Time frame: baseline CMR data
Tissue characterisation
Correlation of segmental perfusion and T1/T2/ECV/LGE
Time frame: baseline CMR data
Cardiovascular Hospitalisation (CVH)
CVH within 12 months
Time frame: 12 months
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