Assessment of Stroke Volume in Shock Using Echocardiography Versus Bioreactive Impedance

N/ARecruitingNCT07020637

University of Nevada, Las Vegas100 enrolled

Overview

This study aims to evaluate the correlation between stroke volume measurements obtained by transthoracic echocardiography and bioreactance-based noninvasive cardiac output monitoring. The primary objective is to assess the level of agreement between these two modalities in critically ill patients.

In this prospective observational study, patients presenting with clinical signs of shock will be enrolled after obtaining informed consent. Stroke volume (SV) will be measured using both transthoracic echocardiography and bioreactance-based noninvasive cardiac output monitoring (Cheetah NICOM). SV will be recorded before and after passive leg raising (PLR) to evaluate the correlation between the two methods in terms of absolute values and directional changes (increase or decrease). No therapeutic intervention will be performed as part of the study; all clinical decisions will remain under the discretion of the treating medical team.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Shock Critical Illness

Interventions

Cheetah NICOMDEVICE

Bioreactance-based noninvasive cardiac output monitoring device used to measure stroke volume before and after passive leg raising. Used solely for observational measurement. No therapeutic intervention is performed.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria * Age ≥ 18 years * Clinical diagnosis of shock as determined by the treating ICU physician (e.g., hypotension requiring vasopressors or evidence of end-organ hypoperfusion) * Able to obtain informed consent from the patient or a legally authorized representative * Enrollment within 24 hours of ICU admission Exclusion Criteria: * Pregnancy * Known severe aortic valve disease or dynamic left ventricular outflow tract obstruction * Morbid obesity (BMI \> 40) that precludes accurate echocardiographic imaging Presence of cardiac arrhythmias (e.g., atrial fibrillation with rapid ventricular response) affecting stroke volume measurements * Implanted cardiac assist devices (e.g., LVAD, pacemaker dependency) * Imminent death or decision for comfort care only

Locations (1)

University Medical Center Southern Nevada

Las Vegas, Nevada, United States

RECRUITING

Outcomes

Primary Outcomes

Correlation Between Stroke Volume Measurements by Echocardiography and Bioreactance Monitoring

Pearson correlation coefficient between stroke volume measurements obtained using transthoracic echocardiography and those obtained using bioreactance-based monitoring (Cheetah NICOM) in response to passive leg raising.

Time frame: Within 1 hour of enrollment

Central Contacts

Mutsumi J Kioka, Medical Doctor

CONTACT

7026712345 mutsumi.kioka@unlv.edu

Office of Research Integrity Human Subjects UNLV

CONTACT

7028952794 IRB@unlv.edu

Data from ClinicalTrials.gov

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