This study will assess the adverse events, tolerability, and how oral doses of ABBV-932 moves through the body in healthy adult Chinese participants.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Enrollment
20
Oral Capsule
Oral Capsule
Shanghai Mental Health Center /ID# 273427
Shanghai, Shanghai Municipality, China
Maximum Plasma Concentration (Cmax) of ABBV-932
Cmax of ABBV-932
Time frame: Up to approximately 43 days
Time to Cmax (Tmax) of ABBV-932
Tmax of ABBV-932
Time frame: Up to approximately 43 days
Observed plasma concentration at the end of a dosing interval (Ctrough) of ABBV-932
Ctrough of ABBV-932
Time frame: Up to approximately 43 days
Area under the plasma concentration-time curve from time 0 until the last measurable concentration (AUCtau) of Desmethyl Cariprazine ABBV-932
AUCtau of ABBV-932
Time frame: Up to approximately 43 days
Maximum Plasma Concentration (Cmax) of DCAR
Cmax of DCAR
Time frame: Up to approximately 43 days
Time to Cmax (Tmax) of DCAR
Tmax of DCAR
Time frame: Up to approximately 43 days
Observed plasma concentration at the end of a dosing interval (Ctrough) of DCAR
Ctrough of DCAR
Time frame: Up to approximately 43 days
Area under the plasma concentration-time curve from time 0 until the last measurable concentration (AUCtau) of Desmethyl Cariprazine (DCAR)
AUCtau of DCAR
Time frame: Up to approximately 43 days
Maximum Plasma Concentration (Cmax) of Didesmethyl-Cariprazine (DDCAR)
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Cmax of DDCAR
Time frame: Up to approximately 43 days
Time to Cmax (Tmax) of DDCAR
Tmax of DDCAR
Time frame: Up to approximately 43 days
Observed plasma concentration at the end of a dosing interval (Ctrough) of DDCAR
Ctrough of DDCAR
Time frame: Up to approximately 43 days
Area under the plasma concentration-time curve from time 0 until the last measurable concentration (AUCtau) of DDCAR
AUCtau of DDCAR
Time frame: Up to approximately 43 days
Number of Participants Experiencing Adverse Events
An AE is defined as any untoward medical occurrence in a patient or clinical investigation participant administered a pharmaceutical product which does not necessarily have a causal relationship with this treatment.
Time frame: Up to approximately 75 days