Augmented Sensory in Cancer-Related Neuropathic Patients"

Isra University, Jordan40 enrolled

Overview

this research studied the effect of augmented sensory feedback program on motor control and risk of falling in patient with CIPN.

Design: A randomized control trial was conducted to investigate the impact of augmented sensory feedback paradigm on motor control and risk of falling in patient with Chemotherapy-induced peripheral neuropathy. Data were collected pre and post treatment from out-patient clinic of the Faculty of Medicine and Faculty of Physical Therapy South Valley University, between January 2023and March 2024. The study was approved by the ethical committee of the Faculty of Physical Therapy, South Vally University, Egypt. The study protocol was explained in detail to every patient and signed written consent was obtained before participation. Participants: forty female patients with CIPN were recruited from out-patient clinic of the Faculty of Medicine and Faculty of Physical Therapy South Valley University, between January 2023and March 2024.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Physical Therapy

Interventions

Gradual Intermittent pneumatic compression therapy (IPC),Balance excercises.PNF techniqueCOMBINATION_PRODUCT

PNF technique

selected physical therapy program as arm excercisesCOMBINATION_PRODUCT

selected physical therapy program only. The program consisted of (core exercises, AROM exercises, and stretching exercises for LL for 18 sessions every other day, over 6 weeks

Eligibility

Sex: FEMALEMin age: 35 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Forty female with age from 35-60 years * clinically diagnosed with CIPN after recovery from stage I or II breast cancer * The strength at the toes, ankles, knees, and hips, as determined by manual muscle tests, of at least 3/5. * The patients can walk independently with or without any assistive devices. Exclusion Criteria: * Patients with a history of hereditary peripheral neuropathy * Diseases that may contribute to peripheral nerve damage, such as diabetes or renal insufficiency, alcohol abuse, HIV, and vasculitis. * Patient who had central or peripheral neurologic disease, brain or spinal cord metastases * Orthopedic problems influencing gait, or foot ulcer at the moment of intake. * Patients with vestibular or neurological problems influencing gait parameters * Subjects who had participated in regular exercise, as defined as 150 min of light-to-moderate intensity exercise per week over the past year, were excluded from this trial.

Locations (1)

Faculty of Physical Therapy South Valley University

Luxor, Qena Governorate, Egypt

Outcomes

Primary Outcomes

improvement of balance which was assessed by fall risk scale

improvement in feet sensitivity and motor control and risk of falling in both groups in favor of the study group.

Time frame: one and half month

Stability measures

postural stability was measured using a Biodex Balance System SD (950-440 with version 4.X software)

Time frame: one and half month

Sensory feedback

Sensory feedback was assessed by using Semmes-Weinstein monofilament (SWM)

Time frame: one and half month

Data from ClinicalTrials.gov

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