Clinical Practices for Treating Severe Malaria Caused by P. Falciparum

Centre Hospitalier de Saint-Denis77 enrolled

Overview

This study looks at how doctors in three hospitals in France treat patients with a serious form of malaria caused by Plasmodium falciparum. It focuses on cases where the level of malaria parasites in the blood is 4% or higher. The study will compare how often a type of medicine called ACT (artemisinin-based combination therapy) is used on its own instead of the usual first-choice treatment (intravenous artesunate), and whether ACT works just as well. It will also check how well patients recover, whether they have complications, and how long they stay in the hospital.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Malaria, Falciparum Plasmodium Falciparum Antimalarials Artemisinins Treatment Outcome Drug Therapy, Combination Retrospective Studies

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients aged 18 years or older. * Diagnosis of Plasmodium falciparum malaria with a parasitemia level ≥ 4%. Exclusion Criteria: \- Patients under 18 years old

Outcomes

Primary Outcomes

Proportion of patients treated with artemisinin-based combination therapy (ACT) alone for Plasmodium falciparum malaria with parasitemia ≥4%.

Time frame: 1 month