Respiratory Function and Oxygenation in Smokers and Non-smokers

Kirsehir Ahi Evran Universitesi42 enrolled

Overview

This study aimed to compare respiratory function, exercise capacity, and intercostal muscle oxygenation in healthy smokers and non-smokers.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Smoking, Tobacco

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria (Smokers): * According to the World Health Organization and ICD smoking addiction criteria, consuming at least one cigarette every day for the last year * Volunteering to participate in research * Able to walk and cooperate Exclusion Criteria (Smokers): * Having any cardiopulmonary disease * Having a musculoskeletal problem that could affect the tests * Failure to comply with tests Inclusion Criteria (Non-smokers): * According to the World Health Organization and ICD smoking addiction criteria, having never smoked or not having smoked in the last year * Volunteering to participate in research * Able to walk and cooperate Exclusion Criteria (Non-smokers): * Having any cardiopulmonary disease * Having a musculoskeletal problem that could affect the tests * Failure to comply with tests

Locations (1)

Kirsehir Ahi Evran University

Kırşehir, Turkey (Türkiye)

RECRUITING

Outcomes

Primary Outcomes

Forced vital capacity

Forced vital capacity (FVC) will be assessed using spirometry.

Time frame: 1st day

Forced expiratory volume in one second

Forced expiratory volume in one second (FEV1) will be assessed using spirometry

Time frame: 1st day

Forced expiratory volume in one second/forced vital capacity ratio

Forced expiratory volume in one second/forced vital capacity ratio will be assessed using spirometry.

Time frame: 1st day

Peak expiratory flow

Peak expiratory flow (PEF) will be assessed using spirometry.

Time frame: 1st day

Forced mid-expiratory flow

Forced mid-expiratory flow (FEF25-75) will be assessed using spirometry.

Time frame: 1st day

Inspiratory muscle strength

Strength index will be evaluated.

Time frame: 1st day

Exercise capacity

will be evaluated with 6 minute walk test and total distance will be recorded.

Time frame: 2nd day

Intercostal muscle oxygenation

During the 6-minute walking test, oxygenation of the intercostal muscles will be evaluated with a monitor.

Time frame: 2nd day

Central Contacts

Merve Firat

CONTACT

+90 850 441 02 44 mervefirat@ahievran.edu.tr

Data from ClinicalTrials.gov

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