Long-term Effects of Lipoabdominoplasty on Pulmonary Function and Sleep Apnea Risk in Obese Subjects

Atlas University24 enrolled

Overview

This study investigates the long-term effects of lipoabdominoplasty on pulmonary function and obstructive sleep apnea (OSA) risk in obese patients. Participants were evaluated before and three months after surgery using spirometry, mMRC dyspnea scores, Epworth Sleepiness Scale (ESS), and STOP-Bang questionnaires.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Obesity Obstructive Sleep Apnea

Interventions

LipoabdominoplastyPROCEDURE

Combination of liposuction and abdominoplasty under general anesthesia. Klein solution used for tumescent liposuction. Muscle plication performed with 0 loop polydioxanone suture. Umbilicus preserved and repositioned. Postoperative compression corset used for 1 month.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥ 18 years * BMI ≥ 30 kg/m² * Eligible for lipoabdominoplasty * Voluntary informed consent Exclusion Criteria: * Pregnancy * Active pulmonary infections or chronic lung disease * Additional surgical interventions during study period * Refusal to participate or incomplete data

Locations (1)

Istanbul Atlas University

Istanbul, Turkey (Türkiye)

Outcomes

Primary Outcomes

Forced Vital Capacity (FVC)

Forced Vital Capacity will be measured before six-minute walk test according to the guideline of ERS.

Time frame: 8-10 minutes

Forced Expiratory Volume in 1 second (FEV1)

Forced Expiratory Volume in 1 second will be measured before six-minute walk test according to the guideline of ERS.

Time frame: 8-10 minutes

Peak Expiratory Flow (PEF)

Peak Expiratory Flow will be measured before six-minute walk test according to the guideline of ERS.

Time frame: 8-10 minutes

Forced Expiratory Flow 25-75% (FEF25-75)

Forced Expiratory Flow 25-75% will be measured before six-minute walk test according to the guideline of ERS.

Time frame: 8-10 minutes

mMRC Dyspnea Score

The dyspnea score will be assessed with the mMRC dyspnea score and is based on five stages of dyspnea caused by exertion and is scored between 0-4.

Time frame: 8-10 minutes

Sleep Apnea Risk Score

Sleep apnoea risk will be assessed using the Epworth Sleepiness Scale (ESS), a validated 8-item questionnaire that measures the subject's likelihood of falling asleep during daily activities. Higher scores reflect greater levels of daytime sleepiness and increased risk for conditions such as obstructive sleep apnoea.

Time frame: 8-10 minutes

Obstructive Sleep Apnea Risk Score

Obstructive sleep apnoea risk will be assessed assessed using the STOP-Bang questionnaire, an eight-item screening tool that evaluates snoring, tiredness, observed apnoea, high blood pressure, BMI, age, neck circumference, and gender. A higher score indicates a greater risk of OSA, with a cut-off of ≥3 commonly used to identify high-risk individuals.

Data from ClinicalTrials.gov

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