"Efficacy of Local Anesthetic for Postoperative Pain in Gynecologic Laparoscopy"

Usama Ahmed Elsaeed Salem, MD90 enrolled

Overview

This is a randomized, double-blind, controlled clinical trial evaluating the efficacy of local anesthetic (LA) in reducing postoperative pain in patients undergoing gynecologic laparoscopic surgery. Ninety participants will be randomly assigned into three equal groups: Group A will receive LA injection at the port site, Group B will receive intraperitoneal LA injection, and Group C will serve as the control group with no LA intervention. Postoperative pain will be assessed and compared among the three groups.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Gynecologic Laparoscopic Surgery Postoperative Pain Recovery Outcomes Pain Management

Bupivacaine 0.25%DRUG

At the end of gynecologic laparoscopic surgery and prior to trocar removal, 40 mL of Bupivacaine 0.25% is instilled intraperitoneal under direct vision to evaluate its analgesic effect.

Bupivacaine 0.25%DRUG

Before trocar insertion in gynecologic laparoscopic surgery, 5 mL of Bupivacaine 0.25% is infiltrated subcutaneously at each trocar port site to assess its effect on postoperative pain.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: Female participants aged 18 to 60 years Scheduled for elective gynecological laparoscopic procedures, including: Evaluation for primary or secondary infertility Assessment of suspected uterine pathology Evaluation of Müllerian anomalies Assessment of suspected tubal or peritoneal pathology requiring diagnostic exploration. Exclusion Criteria: Known allergy or hypersensitivity to local anesthetics (e.g., lidocaine or bupivacaine) Body Mass Index (BMI) ≥ 35 kg/m² Severe hepatic or renal impairment Chronic pain conditions requiring regular opioid use History of major abdominal surgery Refusal to provide informed consent or to enroll in the study

Outcomes

Primary Outcomes

Postoperative Pain score assessed using the Visual Analog Scale .

Postoperative pain will be assessed using the Visual Analog Scale (VAS), ranging from 0 (no pain) to 10 (worst imaginable pain). Higher scores indicate worse pain.

Time frame: 24 hours after surgery

Time to First Analgesic Request

Time frame: 24 hours after surgery

Secondary Outcomes

Total Analgesic Consumption

Time frame: within 24 hours after surgery

Patient Satisfaction Score

Patient satisfaction will be measured using a10- point Likert Scale, where 1 = Very Dissatisfied and 10 = Very Satisfied. Higher scores indicate greater satisfaction.

Time frame: 24 hours postoperatively

Length of Hospital Stay

The duration (in hours) from the end of surgery to the time of hospital discharge will be recorded. This outcome measures the efficiency of recovery and readiness for discharge.

Time frame: From end of surgery until hospital discharge assessed up to 7 days

Time to First Patient Ambulation

Time frame: Within 24 hours after surgery