Gingival enlargement is a common condition caused by increased cell numbers, leading to connective tissue expansion. It can hinder plaque control and cause aesthetic and functional problems, often requiring surgical intervention. Gingivectomy is the primary procedure for treating gingival enlargement, ensuring periodontal health. Postoperative low-level laser therapy (LLLT) may reduce inflammation, relieve pain, and accelerate tissue regeneration. Similarly, hyaluronic acid (HA) stimulates cell proliferation, migration, and differentiation, promoting wound healing. This study aimed to compare the effects of LLLT and HA spray on early wound healing after gingivectomy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
64
940 nm wavelength diode laser was applied to the wound area on the surgery day, 3rd, 5th and 7th days postoperatively. The power of the laser was set to 3W, power density 1.07 W/cm2, probe spot size 2.8 cm2, application mode continuous wave, application distance 1mm and application type stable.
Patients were given a high molecular weight hyaluronic acid spray and instructions for use were explained. Accordingly, the patients applied the spray to the wound area twice a day for the first 7 days.
Akdeniz University
Antalya, Konyaaltı, Turkey (Türkiye)
Visual Analog Score
The Visual Analogue Scale (VAS) is the most common method used to translate values that we cannot measure numerically into numerical form and to measure the severity of acute pain; therefore, the pain felt by the patients in the postoperative period was evaluated using VAS. Patients were given a chart in which a line with a length of 10 cm and a number between 1 and 10 was written on each cm distance and the definitions of the parameter to be evaluated were written and the patient was asked to indicate where his/her condition was appropriate on this line by pointing. On the given scale, 'no pain' was written on '0' end and 'worst pain' was written on the '10' (0: No pain 1-3: Slight pain 3.1-6: Moderate pain 6.1-10: Severe pain), and the patient was asked to mark his/her current pain condition on this line on the 1st day, 3rd day, 7th day and 14th day after the operation.
Time frame: 2 weeks
Wound Healing Area Assessment
At baseline, 3rd day, 7th day and 14th day, the surgical gingivectomy area was disclosed by a erythrosin and gluten-free plaque-disclosing solution to visualize the areas in which the gingival epithelium is absent, abraded or lacking sufficient keratinization and to distinguish these areas from normal gingiva.
Time frame: 2 weeks
Gingival Index
The GI was measured at six sites per tooth, according to Löe \& Silness: 0- Normal gingiva; 1. Mild inflammation with slight color change, mild alteration of gingival surface structure and no bleeding on probing; 2. Moderate inflammation with edema, redness, swelling and bleeding on probing; 3. Severe inflammation with marked edema and redness, ulceration and tendency to bleed spontaneously.
Time frame: 6 weeks
Full Mouth Bleeding Score
FMBS: BoP index is taken as present/absent (+/-) at six sites/teeth, full mouth bleeding score (FMBS) was then calculated as a percentage.
Time frame: 6 weeks
Probing Pocket Depth
Probing pocket depth were taken at six sites/tooth and recorded using a Williams periodontal probe.
Time frame: 6 weeks
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