In cardiac operations, high values of blood lactate have been associated with bad outcomes if detected both during CPB and at the arrival in the intensive care unit (ICU) in adult patients. Many studies highlighted the potential role of hyperlactatemia on admission to the ICU as a marker for adverse outcome, and one study linked hyperlactatemia during CPB with postoperative morbidity and mortality. Evidence that both CENTRAL VENOUS SATURATION (ScVO2) and blood lactates during CPB are potential early predictors of morbidity and mortality in adult cardiac operations are still lacking.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
60
The study will be conducted on cardiac surgical patients who will undergo isolated elective CABG with nonpulsatile flow during cardiopulmonary bypass
The study will be conducted on cardiac surgical patients who will undergo isolated elective CABG with pulsatile flow during cardiopulmonary bypass
effects of pulsatile versus non-pulsatile perfusion methods in CABG surgeries on arterial lactate level.
Arterila Lactate values (mmol/L).
Time frame: 24 hour
effects of pulsatile versus non-pulsatile perfusion methods in CABG surgeries on saturation of central venous blood.
saturation of central venous blood (percentage)
Time frame: 24 hour
The duration of mechanical ventilation (hours).
Time frame: 24 hour
Length of ICU stay (days)
Time frame: 24 hour
Occurrence of major morbidity
The occurrence of at least one in-hospital morbidity with or without in-hospital mortality. (Stroke, seizures, myocardial ischemia, low cardiac output state, post-perfusion syndrome, acute kidney injury, pancreatitis, acute hepatitis, and any other complication will be recorded
Time frame: 72 hours
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