The aim of this study is to compare the efficacy of adding paracetamol to systemic non-steroidal anti-inflammatory drugs (NSAIDs) versus adding dexamethasone as local infiltration to paracetamol on post tonsillectomy pain control.
A Prospective Randomized Controlled study. The study will be conducted at Ain Shams University hospital, Otolaryngology Department. Study period is 6 months from approval of the protocol. Study Participants will be recruited from outpatient ENT clinic, and ENT department inpatients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
75
1- First group: will receive local infiltration of steroids (dexamethasone) in tonsillar bed and paracetamol.
2- Second group: will receive systemic nonsteroidal anti-inflammatory drugs in the analgesic and anti-inflammatory dosage and paracetamol.
3- Third group: control group will receive NSAIDs, steroids and paracetamol as standard post tonsillectomy medications in our department.
Ainshams university hospitals
Cairo, Egypt
RECRUITINGpost tonsillectomy pain
The primary endpoints that will be used is resting pain scores using virtual analogue scale; VAS score (0: no pain-10: worst pain) at DAY 0 after 6h, 24h and DAY 5 post-operatively. Where pain score will be measured at multiple points during the outcome intervals, the pain scores at the time closest to six and 24h will be used.
Time frame: DAY 0 6h, 24h post-operatively and DAY 5 post-operatively
Additional pain medication needed
The percentage of the patients in group 1 and 2 that will need extra analgesia
Time frame: 2 weeks post operatively
Pt feedback after tonsillectomy
Patient satisfaction and return to normal activity.
Time frame: 2 weeks post operatively
Complications
Adverse effects noticed such as nausea, vomiting, infection and post tonsillectomy bleeding.
Time frame: 2 weeks post operatively
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