DeepPriorCBCT for Low Dose Lung CBCT Reconstruction

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology138 enrolled

Overview

The goal of this clinical trial is to learn if the DeepPriorCBCT model ensure high-quality CBCT image while reducing CBCT radiation dose. The main questions it aims to answer are: * Can DeepPriorCBCT reduce CBCT radiation doses? * Is the image quality of DeepPriorCBCT reconstruction consistent with that of existing clinical reconstruction method? Researchers will compare CBCT images quality reconstruction with DeepPriorCBCT model to CBCT image quality reconstruction with existing clinical protocols to see if DeepPriorCBCT model can improve the CBCT image quality while reducing radiation dose. Participants will: * Receive a single low dose (1/6 of existing clinical protocols) CBCT scan * Receive a single conventional dose CBCT scan

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

DOUBLE

Enrollment

138

Conditions

Lung Nodules

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Participants will receive percutaneous thoracic puncture under the guidance of CBCT during the study period. 2. The participants' medical records containing basic information, medical history, etc are complete. 3. Participants can understand the study's purpose, procedures, potential risks, and benefits, and voluntarily signs a written informed consent form. Exclusion Criteria: 1. Participants are under the age of 18. 2. Participants are suffering from severe mental illness or cognitive impairment, unable to understand the study and sign. 3. Participants are pregnant or breastfeeding women. 4. Participants are concurrent participating in other programs that affect the results of this study.

Locations (5)

The First Affiliated Hospital East Campus of Zhengzhou University

Zhengzhou, Henan, China

The First Affiliated Hospital of Zhengzhou University

Zhengzhou, Henan, China

Wuhan Union Hospital

Wuhan, Hubei, China

Wuhan Union Jinyin Lake Hospital

Wuhan, Hubei, China

Wuhan Union West Hospital

Wuhan, Hubei, China

Outcomes

Primary Outcomes

CBCT Images Quality Score

CBCT Images Quality Score was analyzed by 5 radiologists using 5-point Likert scale.

Time frame: No more than 1 week

Secondary Outcomes

The scores of lesion diagnosis from 5 radiologists

5 radiologists from 5 medical centers will be invited to diagnosis the lesion of fully sampled machine-reconstructed CBCT images vs. undersampled model-reconstructed CBCT images.

Time frame: No more than 1 week

The agreement scores given by the 25 interventionalists.

25 interventionalists from 5 medical centers will be invited to analyze fully sampled machine-reconstructed CBCT images vs. undersampled model-reconstructed CBCT images. The scores given by the 25 interventionalists will be used for agreement score analysis.

Time frame: No more than 1 week.

Radiation dose

Radiation dose is defined as the radiation dose received by patients when undergoing one conventional-dose CBCT scan and one undersampled CBCT scan.

Time frame: No more than 1 day