The treatment of persistent lumbar radicular pain (LRP) using CT-guided epidural steroid injection (ESI) is widely used and associated with rare but serious complications. Platelet-rich plasma (PRP), which has recently been shown to promote healing and the anti-inflammatory process by delivering growth factors and cytokines, could be an alternative and potentially safer option. A previous study showed that PRP was as effective as ESI in treating this condition, without major complications. This study aims to compare these two treatments over the long term (2 years).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
200
Intervention consists of interlaminar CT guided epidural steroid injection
Intervention consists of interlaminar CT guided epidural platelet-rich plasma injection after recovery of plasma by blood sampling and centrifugation
Clinique du Sport
Mérignac, France
RECRUITINGFunctional ability
Oswestry Disability Questionnaire ranging from 0 to 100%
Time frame: 30 minutes before procedure ; 6 weeks after procedure ; 6 months, 1 year, 2 years after procedure
Pain evaluation
Numerical pain rating scale (NRS): intensity of combined pain in the legs and back ranging from 0 to 10
Time frame: 6 weeks, 6 months, 1 year and 2 years after procedure
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