Sarcopenia and Peripheral Artery Disease With Chronic Limb Threatening Ischemia

Fudan University97 enrolled

Overview

To evaluate the correlation of Sarcopenia Parameters and Peripheral Artery Disease with chronic limb threatening ischaemia.

Prior researches indicated a relatively high prevalence of sarcopenia among patients of Peripheral Artery Disease. However, the relationship between sarcopenia and progression of Peripheral Artery Disease with chronic limb threatening ischaemia remained poorly understood. Thus, this cohort study aimed to evaluate the correlation of Sarcopenia Parameters, such as psoas muscle area (PMA) and total abdominal muscle area (TAMA) at the L3 vertebral level, measured by computed tomography (CT), and progression of Peripheral Artery Disease with chronic limb threatening ischaemia.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Sarcopenia Peripheral Arterial Disease Chronic Limb Threatening Ischemia

Interventions

Not applicable- observational studyOTHER

non-applicable

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Patients of Peripheral Artery Disease, including intermittent claudication and Chronic Limb Threatening Ischemia; * Patients with Rutherford grade 2-6 between Jan.1 2023 and Dec.31 2024; * Patients at age 18-80; * Patients underwent an in-hospital routine enhanced whole abdomen to lower extremities CT scan; * Patients able to complete the clinical follow-up for 3 months. Exclusion Criteria: * Poor CT quality or incomplete images; * Incomplete clinical data; * In-hospital mortality during Jan.1 2023 and Dec.31 2024.

Locations (1)

Huadong Hospital, Fudan University

Shanghai, China

Outcomes

Primary Outcomes

psoas muscle area (PMA) [measured by computed tomography (CT)]

psoas muscle area (PMA) (square centimeters) was regarded as a kind of typical sarcopenia parameters, measured by computed tomography (CT) at the L3 vertebral level

Time frame: 2023.1.1～2024.12.31

total abdominal muscle area (TAMA) measured by computed tomography (CT)

total abdominal muscle area (TAMA) (square centimeters) was regarded as a kind of typical sarcopenia parameters, measured by computed tomography (CT) at the L3 vertebral level

Time frame: 2023.1.1～2024.12.31

Data from ClinicalTrials.gov

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