Immune-Nutritional Scores and Sleep Quality After Total Abdominal Hysterectomy

N/ANot Yet RecruitingNCT07038564

Istinye University60 enrolled

Overview

This prospective observational study aims to evaluate the relationship between preoperative immune-nutritional status and postoperative sleep quality in women undergoing total abdominal hysterectomy under general anesthesia. Immune-nutritional scores, including the Prognostic Nutritional Index (PNI) and Hemoglobin-Albumin-Lymphocyte-Platelet (HALP) score, will be calculated using routine preoperative blood parameters. Postoperative sleep quality will be assessed using the Richards-Campbell Sleep Questionnaire (RCSQ). Secondary outcomes include postoperative pain scores and patient satisfaction. The study will enroll 60 patients and seeks to determine whether preoperative physiological markers can predict subjective recovery parameters such as sleep and comfort, potentially contributing to personalized perioperative care.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Immune-Nutritional Indexes (PNI, HALP)Postoperative Sleep Quality

Interventions

Immune-Nutritional Scoring and Postoperative Sleep Assessment

Routine preoperative laboratory data (hemoglobin, albumin, lymphocyte, platelet) will be used to calculate immune-nutritional scores (HALP, PNI). Postoperative sleep quality will be assessed with the Richards-Campbell Sleep Questionnaire (RCSQ).

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Female patients aged 18-70 * ASA physical status I-III * Undergoing elective total abdominal hysterectomy under general anesthesia * Available complete blood count and biochemistry results within 24 hours preoperatively * Planned to stay at least one night postoperatively * Sufficient cognitive ability to understand and complete questionnaires * Provided written informed consent Exclusion Criteria: * History of neurological or psychiatric illness * Diagnosed sleep disorders * Current use of sedative or hypnotic medications * Undergoing additional surgical procedures during operation * Requiring postoperative intensive care * Operated under spinal or epidural anesthesia

Outcomes

Primary Outcomes

Postoperative Sleep Quality Score

Sleep quality will be measured using the Richards-Campbell Sleep Questionnaire (RCSQ), a validated 5-item instrument assessing sleep depth, latency, number of awakenings, efficiency, and overall quality. Each item is scored from 0 to 100, with higher scores indicating better sleep quality.

Time frame: Postoperative first night

Secondary Outcomes

Postoperative Pain Score

Pain levels will be assessed using the Visual Analog Scale (VAS), ranging from 0 (no pain) to 10 (worst pain imaginable). Scores will be recorded at rest and during mobilization on each postoperative day.

Time frame: Post-anesthesia care unit (PACU), postoperative day 1 and day 2 (rest and mobilization)

Patient Satisfaction Score

Overall patient satisfaction with the perioperative experience will be assessed using a 0-10 numeric rating scale, with higher scores indicating greater satisfaction.

Time frame: Postoperative day 2