Effect of Modified Poco-Poco Exercise to Aging Biomarkers in Elderly

Universitas Padjadjaran34 enrolled

Overview

Subject with sarcopenia get modified poco-poco exercise program for 12 weeks

34 participants (\>60 years) with sarcopenia were modified poco-poco exercises three times weekly for 12 weeks will assessed sarcopenia staging (determined by assessing skeletal muscle index, muscle strength, physical performance) and levels of global DNA methylation and GDF-15.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Geriatrics Rehabilitation

Interventions

Modified poco-poco exercisesPROCEDURE

Participants performed modified poco-poco exercises three times weekly for 12 weeks

Eligibility

Sex: ALLMin age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age above 60 years old * Have sarcopenia (based on AWGSOP 2019 criteria) Exclusion Criteria: * Hearing impairment/loss hindering participants to receive verbal instructions * Vision impairment/loss hindering participants to receive instructions * Musculoskeletal impairment or severe joint diseases (i.e. deformity in Osteoarthritis or Rheumatoid Arthritis) * Participants have been involved in other exercise program * Severe cardiovascular disease diagnosed by Cardiologist. * Participants will be excluded from the research if they skip 3 sessions of the program consecutively or skip 5 sessions cumulatively

Locations (1)

Hasan Sadikin General Hospital

Bandung, Indonesia

RECRUITING

Outcomes

Primary Outcomes

Sarcopenia Staging (Skeletal Muscle Index)

Skeletal muscle index

Time frame: 12 weeks

Sarcopenia Staging (Muscle Strength)

Hand Grip Strength, score in kilograms

Time frame: 12 weeks

Sarcopenia Staging (Physical Performance)

Short Physical Performance Battery, score in numerical 0-12

Time frame: 12 weeks

Levels of Global DNA Methylation

Global DNA methylation levels were analyzed using the ELISA-based kit

Time frame: 12 weeks

Levels of Growth Differentiation Factor 15

Growth Differentiation Factor 15 were analyzed the Quantikine ELISA Human GDF-15 Immunoassay

Time frame: 12 weeks

Central Contacts

Irma Ruslina Defi

CONTACT

+622284288888 irma.ruslina@unpad.ac.id

Irma Ruslina Defi

CONTACT

Data from ClinicalTrials.gov

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