Effects of Pulmonary Resection on Right Ventricular Function

Çağrı Özdemir25 enrolled

Overview

Lung resection is associated with high postoperative morbidity and mortality and leads to a significant long-term decrease in functional capacity, particularly due to cardiorespiratory complications. One of the contributing factors to this functional decline is the postoperative reduction in right ventricular function. Due to the anatomical proximity and interactions, right ventricular function is evaluated by echocardiography following lung resection. The pulmonary artery pressure (PAP)/tricuspid annular plane systolic excursion (TAPSE) ratio is a parameter that provides a more comprehensive assessment of right heart function by evaluating both right ventricular systolic function and pulmonary artery pressure. In this study, investigators aimed to evaluate changes in right heart function by performing preoperative and postoperative echocardiographic assessments in participants undergoing lung resection, focusing on PAP/TAPSE ratios.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Pulmonary Resection Right Ventricular Function Echocardiography Cardiothoracic Anesthesia

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: Adults aged 18 to 80 years ASA classification I-III Patients scheduled to undergo lung resection in thoracic surgery Exclusion Criteria: Patients with arrhythmia Patients using antiarrhythmic drugs Patients with renal failure requiring hemodialysis Patients with a history of previous lung surgery Patients with valvular heart disease Patients with a history of angina pectoris or myocardial infarction within the past month Patients with FEV1/FVC ratio below 60%

Outcomes

Primary Outcomes

Echocardiographic Assessment: TAPSE/PAP Ratio

Patients will be evaluated by echocardiography 24 hours before surgery and on the second postoperative day, and the TAPSE/PAP ratio will be recorded in mm/mmHg.

Time frame: 24 hours preoperatively and on postoperative day 2

Echocardiographic Assessment: Tricuspid Annular Plane Systolic Excursion (TAPSE)

Patients will be evaluated by echocardiography 24 hours preoperatively and on postoperative day 2, and TAPSE will be recorded in millimeters (mm).

Time frame: 24 hours preoperatively and on postoperative day 2

Echocardiographic Assessment: Pulmonary Artery Pressure (PAP)

Patients will be evaluated by echocardiography 24 hours before surgery and on the second postoperative day, and PAP will be recorded in millimeters of mercury (mmHg).

Time frame: 24 hours preoperatively and on postoperative day 2

Effects of Pulmonary Resection on Right Ventricular Function

Overview

Conditions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Central Contacts