Patients with acute ischemic stroke who have undergone endovascular thrombectomy will be eligible to be included, and thrombus will be collected after obtaining informed consent. Enrolled patients will receive a comprehensive diagnostic evaluation and the best medical treatment according to recent stroke management guidelines. The mechanism of the stroke will be classified into atherosclerotic, cardiac embolism, others and unknown causes based on diagnostic workup. Patients will be monitored in an outpatient clinic for vascular events including stroke recurrence, death, and bleeding events, which will continue for up to two years after the initial stroke event. Thrombus information related to RNA expression patterns and histological characteristics will be analyzed to classify the stroke mechanism and predict future vascular events after the initial stroke.
Study Type
OBSERVATIONAL
Enrollment
500
Detailed expression pattern of RNA and histological characteristics will be investigated.
Seoul National University Hospital
Seoul, Jong-ro Gu, South Korea
RECRUITINGVascular events
major vascular events after endovascular thrombectomy, including stroke, myocardial infarction, and vascular death
Time frame: two years after initial stroke
Thromboembolic events
Any thromboembolic events after endovascular thrombectomy including ischemic stroke, transient ischemic attack, myocardial infarction or unstable angina, peripheral artery disease requiring hospitalization, venous thromboembolism, pulmonary embolism and vascular death
Time frame: two years after initial stroke
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