Analysis of Cerebrospinal Fluid in Patients With Cerebral Toxoplasmosis at CHSD (2004-2024)

Centre Hospitalier de Saint-Denis53 enrolled

Overview

This study looks at patients who were treated for cerebral toxoplasmosis at CHSD between 2004 and 2024. It focuses on analyzing their cerebrospinal fluid (CSF) to better understand the biological signs of the disease. The goal is to see if CSF results can show signs of meningitis, even though it's not commonly reported, and to describe any co-infections, symptoms, brain imaging findings, and patient outcomes.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Toxoplasmosis, Cerebral Toxoplasmosis Meningitis HIV Infections Cerebrospinal Fluid Central Nervous System Infections

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: \- Adult patients (age 18 years) hospitalized at CHSD between January 1, 2004 and March 31, 2024 for cerebral toxoplasmosis Exclusion Criteria: \- Under 18 years ols

Outcomes

Primary Outcomes

Number of participants with treatment-related adverse events as assessed by CTCAE v4.0

Time frame: From hospital admission to completion of diagnostic lumbar puncture and initial treatment (typically within the first 7 days of hospitalization).