Blood Flow Restricted Resistance Exercises Versus Low Level Laser on Cardiac Functions in Patients With Chronic Heart Failure

Cairo University60 enrolled

Overview

This study is designed to compare between blood flow restricted resistance exercises and low level laser on cardiac functions in patients with chronic heart failure

This study will be carried out on sixty male and female patients diagnosed with chronic heart failure. They will be recruited from El-Demerdash hospital, Ain Shams university, Cairo. Their ages will be ranged from (40-60) years old. The design of this study will be a randomized controlled trail (RCT). The patients of this study will randomly assigned into three equal groups (n=20): Study Group A (20 patients) will receive blood flow restricted resistance exercises in addition to medical treatment program and routine cardiac rehabilitation. Study Group B (20 patients) will receive low level laser in addition to medical treatment program and routine cardiac rehabilitation. Control Group C (20 patients) will receive medical treatment program and routine cardiac rehabilitation only. The program of treatment for the three groups A ,B , and C will be applied once per day, three times per week for 12 consecutive weeks

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Heart Failure NYHA Class II

Interventions

Acupuncture LLLT:DEVICE

Acupuncture LLLT: This mode of therapy will be conducted for study group B as follows: A therapeutic unit (M6 MLS from ASA laser, Italy) with wavelength 905 nm, output 5-20 MW, laser beam spot size 0.785 cm2, energy density 91 J/cm2, energy delivered 28 J, and frequency 500HZ. Laser probe will be placed in intercostal space both anteriorly and posteriorly on chest wall. Each acupuncture point will be stimulated with a laser for 60 s, three weekly sessions over 12 successive weeks. Anterior chest wall acupuncture points are {LU1, LU2, CV17, (Ren17)}, posterior chest wall from a prone or setting position of the patient {UB13, (BL13), UB 17(BL17)}.

Blood flow restricted resistance exercise:OTHER

The subject will warm up and cool down for at least five to seven minutes each, (before and after exercise). The patients will perform blood flow restricted resistance exercise (BFRRE) at 40-80% of 1RM with 50% limb occlusion pressure (LOP), while placing cuff on midthigh and perform four sets of bilateral knee extension exercise, each set consist of 15 repetitions with 30-60 second rest in between sets and relieve cuff pressure in rest period, three weekly sessions over 12 successive weeks

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Sixty male and female patients diagnosed with chronic heart failure since six months with LVEF\<40%. * They are functionally classified as class II according to New York Heart Association (NYHA). * Their age will be ranged from 40 to 60 years old. * Their BMI will be ranged from 25 to 29.9 kg/m². * They will have good mentality Exclusion Criteria: * Unstable coronary heart disease. * Severe valvular diseases. * Underlying pulmonary disease (aspiration pneumonia, chronic obstructive pulmonary disease, pneumothorax, etc.). * Inability to ambulate owing to physical problems (paresis induced by cerebral stroke, spinal cord injury, amputation, severe pain, dyspnea, etc.). * muskloskletal problems (e.g. severe osteoarthritis or ankylosing spondylitis). * impaired cognitive function (vascular dementia, Alzheimer's dementia, other psychological disease, etc.)

Locations (1)

Cairo University

Giza, Egypt

Outcomes

Primary Outcomes

: speckle-tracking echocardiography - NO Blood analysis

Echocardiography: speckle-tracking echocardiography an advanced, non invasive imaging modality that allow accurate assessment of the global and regional function of both atrial and ventricular chambers based on interaction between myocardial tissue and ultrasound beam. It is possible to obtain the deformation of LV myocardium along longitudinal, circumferential, radial and rotational plane. As longitudinal strain (LS) represents the LV myocardial shortening along its longitudinal axis. Radial strain (RS) reflect radial myocardial deformation corresponding to systolic thickening and is defined by positive curve. Circumferential strain (CR) represents the myocardial shortening along the circumferential plane, normally curves are negative. NO Blood analysis: All blood samples will be collected by venipuncture and immediately will be analyzed with Nitric Oxide Assay Kit (Fluorometric). The Kit is used to measure NO concentration

Time frame: 3 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.