the goal of the clinical trial is to study the effect of aerobic and resistive exercises on atherogenic index in hemodialysis patients the study will include three groups of both sex the first group will participate in aerobic exercise ,the second group will participate in resistive exercise and the third group will be control group
This study will be carried out on sixty male and female patients. They will be recruited from National Institute of Kidney and Urology, Mataria,Their ages will be ranged from (40-60) years old these patients will be assigned into three groups (A, B and C). The design of this study will be a randomized controlled trail (RCT).The patients will be informed about the study procedure and signed the informed consent prepared for this study . The study will follow the instructions of ethical committee of faculty of physical therapy, Cairo University. Inclusive criteria 1. Maintenance hemodialysis ≥ 3 months. 2. BMI will be ranged from 18.5 to 29.9 kg/m². 3. Age ≥ 40years and ≤ 60 years. 4. Hemodialysis 3 times a week. Exclusive criteria: 1. patients suffered from any central and peripheral nervous system diseases. 2. patients suffered from serious complications, such as heart failure, severe infection and malignant tumor. 3. uncontrolled hypertension with systolic blood pressure ⩾200 mm Hg and/or diastolic blood pressure ⩾120 mm Hg, 4. unstable angina
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
60
twenty patients will participate in moderate intensity intradialytic aerobic training for 12 weeks. (3 times per week). Using Horizontal electromagnetically braked cycle ergometer during the first half of the dialysis session. (1) Frequency: received intradialytic, lower-limb, cycling exercise three times per week on alternative days (2) Intensity: the intensity of exercise will be at 12-14 (moderate-intensity: somewhat hard or reports of feeling a little bit tired but still ok to continue) based on the Borg's Perceived Exertion Rating Scale Appendix III (a rating of 6 perceiving "no exertion at all" to 20 perceiving a "maximal exertion" of effort) ,Appropriate speed and grade of resistance were adjusted to achieve the required intensity. (3) Time: the duration of each exercise session consisted of a 5-min warm-up in form of circulatory exercise.
Twenty patients will participate in moderate intensity intradialytic resistive training for 12 weeks. (3 sessions per week) using ankle weights. During session: The warming up phase for 5-minute in form of circulatory exercises, then the main exercise phase and then cooling down phase for 5 minutes. in form of circulatory exercises. The training protocol consisted of five lower-body resistance exercises using ankle weights 3 days/week, The intensity of the program will be moderate, starting with two sets of each exercise at 60% of each patient's three repetition max (3-RM) strength, progressing to three sets per session, with additional weight added as tolerated
National Institute of Kidney and Urology, Mataria
Cairo, Select State, Egypt
NOT_YET_RECRUITINGNational Institute of Kidney and Urology, Mataria
Cairo, Egypt
RECRUITINGatherogenic index
aterogenic index will be measured through blood test ,an AIP value of under 0.11 is associated with low risk of CVD; the values between 0.11 to 0.21 and upper than 0.21 are associated with intermediate and increased risks, respectively
Time frame: three months
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this group will include 20 patients will participate in circulatory exercises and will be evaluated at the beginning and at the end of the study.