Comparison Between Two Blocks in Analgesia After Knee Arthroplasty

N/AActive Not RecruitingNCT07046377

Ain Shams University30 enrolled

Overview

Comparative Study between Adductor canal block combined with infiltration OF The interspace between popliteal artery and the capsule of the knee block versus genicular nerves Block combined with IPACK in Postoperative analgesia after knee replacement surgery

Patient informed written consent and ethical committee approval of Faculty of Medicine; Ain Shams University will be obtained before patient allocation. • Study procedures: Supervisors and experts will do all the study procedures. Patients undergoing unilateral Total knee replacement (TKR) will be randomly assigned into one of the following groups using computer generated codes (15 patients in each group): Group 1 (ACB - IPACK group): will receive spinal anesthesia and ultrasound-guided Adductor canal nerve block, as well as infiltration of the space between the popliteal artery and the capsule of the posterior knee (IPACK) block. Group 2 (GNB - IPACK group): will recieve spinal anesthesia and US guided Genicular nerves block and IPACK block.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Enrollment

Conditions

Post Operative Pain

Interventions

ACB - IPACKPROCEDURE

will receive spinal anesthesia and ultrasound-guided Adductor canal nerve block, as well as infiltration of the space between the popliteal artery and the capsule of the posterior knee (IPACK) block.

GNB - IPACKPROCEDURE

will recieve spinal anesthesia and US guided Genicular nerves block and IPACK block.

Eligibility

Sex: ALLMin age: 30 YearsMax age: 85 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age 30-85 years. * Both sexes. * American Society of Anesthesiologists (ASA) Physical Status Class I to III. * Patients scheduled for unilateral TKA under spinal anesthesia. Exclusion Criteria: * Patient's refusal. * American Society of Anesthesiologists (ASA) Physical Status Class above III. * local infection. * History of allergy to the medications used in the study. 5. Psychiatric disorder.

Locations (1)

Ain shams university

Cairo, Cairo Governorate, Egypt

Outcomes

Primary Outcomes

1- Comparing both groups regarding the time needed ( in hours) for the first call rescue analgesia post operatively.

Total knee replacement (TKR) is a well-known popular surgical procedure for knee diseases, including end-stage knee osteoarthritis that causes severe postoperative pain and prolonged immobility. Acute pain control can be provided with multimodal analgesia, including non-steroidal anti-inflammatory drugs (NSAIDs) and opioids. However, NSAIDs cause many side effects as peptic ulcer and gastritis, also opioids have gastrointestinal side effects as constipation, nausea and vomiting as well as respiratory depression. Regional analgesia has been used as another modality to provide sufficient perioperative pain relief with minimal opioid consumption to avoid it's adverse effects peripheral nerve blocks (PNBs) is a common practice in orthopedic surgery. PNBs provide excellent pain management after TKA, promote early mobilization, and reduce the consumption of opioids, the incidence of opioid-related adverse effects, and the hospital stay

Time frame: 5 minutes after ending of operation

Data from ClinicalTrials.gov

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