Hashimoto's thyroiditis (HT) is an autoimmune disease affecting the thyroid gland and is one of the most common causes of hypothyroidism. Eating habits may affect the risk of several inflammatory and immune diseases, such as HT. The current knowledge of the diet in HT is insufficient. The Mediterranean diet (MD) is an anti-inflammatory diet characterized by frequent consumption of olive oil, unrefined cereals, fresh or dried fruit and vegetables, moderate amounts of fish, dairy, and meat, and many condiments and spices. It is rich in nutrients and bioactives, which have the potential to offer anti-inflammatory aspects.
The investigators aimed to assess the impact of the Mediterranean diet on patients with Hashimoto thyroiditis using the following outcomes: Primary outcomes: Anti-TPO antibodies, Anti-Thyroglobulin antibodies, TSH, T3, T4 Secondary outcomes: BMI, Lipid profile, Symptoms of hypothyroidism
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
40
3-month dietary plan
Ain Shams University hospital
Cairo, Egypt
Changes in the serum level of anti-TPO and Anti-TG antibodies
IU/ml
Time frame: after 3 months of dietary modification
Changes in the serum level of TSH
uIU/ml
Time frame: after 3 months of dietary modification
Changes in the serum level of free T3
pg/ml
Time frame: after 3 months of dietary modification
Changes in the serum level of free T4
ng/dl
Time frame: after 3 months of dietary modification
changes in BMI
kg/m\^2
Time frame: after 3 months of intervention
changes in serum level of total cholesterol, triglyceride, low-density lipoprotein, high-density lipoprotein
mg/dl
Time frame: after 3 months of intervention
Symptoms of hypothyroidism
Thypro Scale
Time frame: after 3 months of intervention
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.