Dexmedetomidine Versus Ketamine on Laryngeal Microsurgery

Cairo University168 enrolled

Overview

compare effect of IV dexmedetomidine and ketamine on pain score, perioperative hemodynamics and detect side effects of dexmedetomidine and ketamine.

Microlaryngeal surgery is a common surgical procedure now a days which is associated with many complications such as postoperative pain, airway edema and persistent cough . the study is to compare the effect of IV dexmedetomidine and ketamine on pain score, perioperative hemodynamics and to detect side effects of dexmedetomidine and ketamine.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

168

Conditions

Microlaryngeal Surgery

Interventions

DexmedetomidineDRUG

IV dexmedetomidine

KetamineDRUG

IV ketamine

Saline (control group)DRUG

no drugs

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * aged 18-70 years ASA I,II Exclusion Criteria: * CVdiseases as IHD and severe valvular disease. * allergy to ketamine or dexmedetomidine. * Patients refusal * Suspected difficult intubation more than 2 trials

Locations (1)

Faculty of medicine Cairo university

Cairo, Egypt

Outcomes

Primary Outcomes

incidence of postoperative sore throat

Time frame: 30 minutes postoperative