The primary objective of this study is to determine if the addition of Rocklatan post-Hydrus will provide additional intraocular pressure lowering.
The study is a prospective single-practice with multiple locations, single-surgeon, parallel double arm study in subjects with open angle glaucoma (OAG), who were implanted with Hydrus microstent combined with cataract surgery to be randomized to receive Rocklatan vs. Comparator (artificial tears). Unmedicated MDIOP (mean diurnal intraocular pressure) measurements will be assessed at baseline (after Hydrus, prior to study medication) and at 1-month post-initiation of Study Drop.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
68
Additional intraocular eye pressure lowering post-Hydrus
Placebo Comparator (artificial tears)
Center for Sight
Las Vegas, Nevada, United States
Mean diurnal intraocular pressure change from baseline
After Hydrus prior to study initiation drop
Time frame: After 28 days up to 35 days post initiation of Rocklatan vs placebo comparator
Diurnal Intraocular pressure change from baseline and difference between intraocular pressure at each time point
Goldmann Applanation Tonometry
Time frame: After Hydrus prior to study drop and after 28 days up to 35 days post initiation of study drop for all time points 8am, 10am, 4pm (± 1 hour) between groups
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