Effect of Whole-body Vibration Training in Patients With Renal Dialysis

Cairo University60 enrolled

Overview

To show the effect of whole-body vibration in physical performance in patients with renal dialysis.

By now, safety and efficacy of WBV has not been investigated in patients with ESRD. Therefore, we performed this exploratory study in hemodialysis patients in order to elucidate potential effects of whole-body vibration exercise on physical performance and various biochemical markers in this condition. WBV is extensively studied as a means to prevent microgravity and immobility associated muscle wasting and bone loss in space flight and it is getting increasingly popular even among elderly. Whole-body vibration exercise (WBVE) is a novel exercise protocol designed to prevent the loss of muscle strength and bone mineralization during the immobility and weightlessness of space flight. A situation similar to HD. Vibration exercise uses high-frequency vibration of muscle groups causing positive feedback of the spinal reflex arc and resulting in high levels of muscle contraction to motor unit recruitment. There can be multiple physiological benefits from vibration exercise, including cardiovascular effects, bone health and muscle strength. The advantages of WBV result from the combination of hardly any physical stress for the participants, short duration of intervention and a comparatively high effectiveness. means of exercise that can also be offered to those patients unable or unwilling to perform conventional training.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Renal Dialysis

Interventions

whole body vibrationDEVICE

Whole-body vibration (WBV) is a training method that uses mechanical vibration and external resistance loading to stimulate the body, causing muscle vibration and increasing central nervous system adaptations (Rittweger, 2010).

Eligibility

Sex: MALEMin age: 60 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: All patients that will be included in this study will meet the following criteria: 1. Body mass index (BMI) from 25.0 to 29.9 kg/m2. 2. Quitting smoking for more than 3 months. 3. Their age will be ranged from 60-70 years old. 4. Clinically and medically stable. 5. Hemodialysis treatment over at least 6 months before enrollment. 6. Patients with CKD (systolic blood pressure \< 140 mmHg diastolic blood pressure \< 90 mmHg and heart rate \< 80 bpm). 7. The presence of kidney damage (i.e., albuminuria) or decreased kidney function (i.e. glomerular filtration rate (GFR) \< 60 ml/min per 1-73 m2) for 3 months or more irrespective of clinical diagnosis. \- Exclusion Criteria: Patients will be excluded if they have: 1. Patients with uncontrolled pulmonary disease. 2. Patients with vascular severe complication as critical limb ischemia. 3. Patients with unstable angina, uncontrolled cardiac arrhythmia, decompensated heart failure. 4. Patients with severe musculoskeletal problems (e.g., severe knee osteoarthritis or post knee replacement surgeries). 5. Any patients who missed more than two weeks of the program or want to terminate the program. \-

Locations (1)

Cairo university

Giza, Cairo University, Egypt

Outcomes

Primary Outcomes

bone mineral density

Blood sample to take bone mineral density. (calcium \& phosphorus)

Time frame: 3 months

physical performance

For participant's functional status will be evaluated by a series of physical performance tests

Time frame: 3 months

Data from ClinicalTrials.gov

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