Risk Factors Affecting Mortality in Perforated Peptic Ulcer

Maharajgunj Medical Campus85 enrolled

Overview

Perforation is one of the most severe and life-threatening complications of peptic ulcer disease. This study aims to evaluate the risk factors associated with postoperative morbidity and mortality in patients undergoing surgery for peptic ulcer perforation, with a focus on the timing of presentation, demographic variables, surgical delay, and their association with postoperative outcomes.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Peptic Ulcers

Interventions

Emergency laparotomyPROCEDURE

Emergency laparotomy

Eligibility

Sex: ALLMin age: 15 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with peptic ulcer perforation aged\> 15 years and \<75 years. * Patients with duodenal or gastric perforation of peptic ulcer origin. * Patients who underwent simple closure with omental patch as a standard operative procedure. Exclusion Criteria: * Patients treated with conservative management. * Patients with perforation of peptic ulcer origin at the jejunum, ileum adjacent to Meckel's diverticulum. * Patients presenting with recurrent perforation or stomal ulcer perforation.

Locations (1)

National Medical College and Teaching Hospital

Birgunj, Nepal

Outcomes

Primary Outcomes

Postoperative Morbidity Rate

Incidence of postoperative complications (e.g., wound infection, sepsis, anastomotic leak, pneumonia) in patients undergoing surgery for perforated peptic ulcer.

Time frame: 12 months (from patient enrollment to completion of follow-up)

Postoperative Mortality Rate

Incidence of death following surgical intervention for perforated peptic ulcer.

Time frame: 12 months (from patient enrollment to completion of follow-up)

Data from ClinicalTrials.gov

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