Comparison of the Impact of Different Suspension Mediums on ABO Antibody Titres.

Institute of Liver and Biliary Sciences, India200 enrolled

Overview

Accurate estimation of ABO antibody titres is vital in Transfusion Medicine due to their involvement in hemolytic transfusion reactions, hemolytic disease of the fetus and newborn, and solid-organ transplant rejection. Although the conventional tube technique (CTT) remains the gold standard, its standardization is challenging, partly influenced by the choice of diluents. This study aimed to compare commonly used diluents in ABO antibody titration via CTT and analyze the resulting titre variations.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Healthy Blood Donor

Interventions

Titres on conventional test tube method with different diluentDIAGNOSTIC_TEST

Titres on conventional test tube method with different diluent

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: \- Healthy Blood Donor. Exclusion Criteria: \- Samples from female donors, those with irregular antibodies and reactive to transfusion-transmissible infections on routine testing, were excluded.

Locations (1)

Institute of Liver and Biliary Sciences

New Delhi, National Capital Territory of Delhi, India

Outcomes

Primary Outcomes

Comparison of the ABO Antibody Titres.

Time frame: Day 0

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.