This is a multicenter, randomized, open-label, positive controlled efficacy exploration study. To compare the efficacy and safety of once-weekly GZR102 Injection and Bi-Weekly GZR18 Injection in Chinese adult subjects with type 2 diabetes mellitus (T2DM) and inadequate glycemic control on GLP-1 receptor agonists (GLP-1RAs), with or without oral antidiabetic drugs (OADs).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
90
Study site 01
Beijing, China
efficiency endpoint
Change from baseline in Hemoglobin A1c (HbA1c)%
Time frame: Week 24
efficiency endpoint
Change fom baseline in fasting plasma glucose (FPG)
Time frame: Week 24
hypoglycemic events.
Percent change (%) from baseline in weight
Time frame: Week 24
hypoglycemic events.
Treatment-emergent adverse events (TEAEs)
Time frame: Week 24
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