The goal of this clinical trial is to learn the effect of low level tragus stimulation (LLTS) on echocardiographic parameter in patient with ST-segment Elevation Myocardial Infarction (STEMI) who undergo primart percutaneous coronary intervention (PPCI). It will also learn about the safety of LLTS in such setting. The main questions, it aims to answer are compared with sham control: Does LLTS could alter left ventricular ejection fraction in patients with STEMI? Does LLTS could alter wall motion score index in patients with STEMI? Does LLTS could alter diastolic dysfunction in patients with STEMI? Researchers will compare LLTS to sham LLTS control to see if LLTS have benefit in participants with STEMI participants will divided into two group i.e. treatment group vs control (sham/placebo) group.. Both groups undergo transthoracal echocardiographi examination before and after PPCI..
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
100
Participant will undergo stimulation in their left tragus for 60 minutes by using Parasym device
Participant will undergo implantation of Parasym device lead in their left tragus but without any stimulation for 60 minutes
Dr. Kariadi Central General Hospital
Semarang, Central of Java, Indonesia
RECRUITINGLeft Ventricular Ejection Fraction
Left Ventricular Ejection Fraction measured by transthoracic echocardiography
Time frame: Before PPCI, 1 day after PPCI, and 30 days after PPCI
Wall Motion Score Index
Wall Motion Score Index measured by transthoracic echocardiography
Time frame: Before PPCI, 1 day after PPCI, and 30 days after PPCI
Diastolic Function
Diastolic Function measured by transthoracic echocardiography
Time frame: Before PPCI, 1 day after PPCI, and 30 days after PPCI
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