This study is being done to compare the effect of regular exercise and metformin in people who have prediabetes. It is a community-based, open-label, randomized trial in which eligible participants will be divided into two groups. One group will do moderate physical exercise, and the other group will take metformin for 12 weeks. We will check their fasting blood sugar and HbA1c before and after the treatment to see which method works better for controlling sugar levels. The study is being done in a low-resource community setup to see which option is more practical and effective in real-life Pakistani settings.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
226
Structured moderate-intensity aerobic activity (e.g., brisk walking) for 30-45 minutes/day, 5 days/week, for 12 weeks.
Participants will receive oral metformin 500 mg twice daily for 12 weeks.
Department of Preventive Medicine, Combined Military Hospital Nowshera
Nowshera, Pakistan
Change in Glycated Hemoglobin (HbA1c) from Baseline to 12 Weeks
HbA1c (%) will be measured to assess glycemic improvement following 12 weeks of intervention.
Time frame: Baseline and 12 week
Weight change
Change in weight in kilograms from baseline to 12 weeks following the two interventions
Time frame: Baseline to 12 weeks
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