TTE Improves Clinical Management of Stable Chest Pain

Tianjin Chest Hospital50,000 enrolled

Overview

The investigator aims to prospectively enroll patients who were referred for transthorcic echocardiography (TTE) for the assessment of stable chest pain (SCP) suspected of obstructive coronary artery disease (CAD). All patients underwent TTE according to established guidelines and local institutional protocols. This study will determine if TTE-based imaging evaluation can provide more informaton to improve clinical management for SCP, including fewer MACE and better decision-making of downstream investigations and therapeutic interventions.

Study Type

OBSERVATIONAL

Enrollment

50,000

Conditions

Transthorcic Echocardiography Stable Angina Pectoris Coronary Artery Disease Major Adverse Cardiac Events Invasive Coronary Angiography

Interventions

All patients underwent TTE according to established guidelines and local institutional protocols. The imaging data were evaluated using different image post-processing software to comprehensively analyse anatomical, functional and histological information of coronary.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * symptomatic patients with SCP suspected of obstructive CAD. * referred for TTE for the assessment of SCP. * ≥18 years of age. * signed informed consent. Exclusion Criteria: * acute coronary syndromes * previous CAD or coronary revascularization * nonsinus rhythm * cardiomyopathy, valvular disease, congenital heart disease or left cardiac insufficiency because of other reasons

Outcomes

Primary Outcomes

Major adverse cardiovascular events

Time frame: 10 years

Secondary Outcomes

Invasive coronary angiography

Invasive coronary angiography occurred at follow-up after TTE, attributed to TTE results or unplanned.

Time frame: 10 years

Medication prescription

Change for medication prescription of antiplatelet agents, anti-ischemic drugs, lipid-lowering agents, angiotensin-converting enzyme inhibition and so on, attributed to TTE results or unplanned,

Time frame: 10 years

Coronary revascularization

PTCA, PCI or CABG occurred at follow-up after TTE, attributed to TTE results or unplanned.

Time frame: 10 years

TTE Improves Clinical Management of Stable Chest Pain

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Secondary Outcomes

Central Contacts