The goal of this interventional clinical trial is to learn whether Cationorm can improve symptoms after pterygium surgery. The main question it aims to answer is what is the level of improvement of symptoms after pterygium surgery. Researchers will compare with other artificial tears (hyaluronic acid, polymers or cellulose derivatives eye drops) arm to see if Cationorm is similar or superior in terms of improvement of symptoms after pterygium surgery. Participants will * Take 1 drop Cationorm/artificial tear before and after surgery and during follow up. * Visit for checkups after 7 days
Participants will take: * Before surgery: 1 drop Cationorm/artificial tear at the eye that will undergo surgery * After surgery: 1 drop Cationorm/artificial tear at the eye that underwent surgery before eye bandages * Follow up after surgery: 1 drop Cationorm/artificial tear 4-6 times/day alternating with antibiotics (third-fourth generation quinolone) with 2-hour interval between drops * Maintenance phase: 7-14 days with the same regimen * After day 5, if fluorescein staining (-), can add corticosteroid monotherapy or addition with antibiotics * After 5 days of surgery, can add more antibiotics depend on the symptoms of patients
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
100
Cationorm single-dose eye drop is a preservative-free, cationic oil-in-water nano-emulsion.
Artificial tear eye drops are hyaluronic acid, polymers or cellulose derivatives eye drops
Ba Ria - Vung Tau Eye Hospital
Bà Ria, Ba Ria - Vung Tau, Vietnam
Frequency and Severity of Blurred Vision symptom
All study outcomes are collected using modified OSDI questionnaire answered by patients before surgery, after surgery and 7 days after surgery. These outcomes includes the frequency and severity of: * Symptoms: Blurred Vision, Eye Pain, Watery Eyes, Itchiness, Grittiness, Sensitivity to Light * Impact on daily life activities: Discomfort when Reading, Discomfort when Watching TV, Discomfort when Using Computer, Discomfort when Driving at Night, Discomfort when Being Outdoors, Discomfort when Being in Air-Conditioned Areas Frequency: Never, Some of the time, Most of the time, All of the time Severity: None, Mild, Moderate, Severe
Time frame: From enrollment to 7 days after surgery
Frequency and Severity of Eye Pain symptom
All study outcomes are collected using modified OSDI questionnaire answered by patients before surgery, after surgery and 7 days after surgery. These outcomes includes the frequency and severity of: * Symptoms: Blurred Vision, Eye Pain, Watery Eyes, Itchiness, Grittiness, Sensitivity to Light * Impact on daily life activities: Discomfort when Reading, Discomfort when Watching TV, Discomfort when Using Computer, Discomfort when Driving at Night, Discomfort when Being Outdoors, Discomfort when Being in Air-Conditioned Areas Frequency: Never, Some of the time, Most of the time, All of the time Severity: None, Mild, Moderate, Severe
Time frame: From enrollment to 7 days after surgery
Frequency and Severity of Watery Eyes symptom
All study outcomes are collected using modified OSDI questionnaire answered by patients before surgery, after surgery and 7 days after surgery. These outcomes includes the frequency and severity of: * Symptoms: Blurred Vision, Eye Pain, Watery Eyes, Itchiness, Grittiness, Sensitivity to Light * Impact on daily life activities: Discomfort when Reading, Discomfort when Watching TV, Discomfort when Using Computer, Discomfort when Driving at Night, Discomfort when Being Outdoors, Discomfort when Being in Air-Conditioned Areas Frequency: Never, Some of the time, Most of the time, All of the time Severity: None, Mild, Moderate, Severe
Time frame: From enrollment to 7 days after surgery
Frequency and Severity of Itchiness symptom
All study outcomes are collected using modified OSDI questionnaire answered by patients before surgery, after surgery and 7 days after surgery. These outcomes includes the frequency and severity of: * Symptoms: Blurred Vision, Eye Pain, Watery Eyes, Itchiness, Grittiness, Sensitivity to Light * Impact on daily life activities: Discomfort when Reading, Discomfort when Watching TV, Discomfort when Using Computer, Discomfort when Driving at Night, Discomfort when Being Outdoors, Discomfort when Being in Air-Conditioned Areas Frequency: Never, Some of the time, Most of the time, All of the time Severity: None, Mild, Moderate, Severe
Time frame: From enrollment to 7 days after surgery
Frequency and Severity of Grittiness symptom
All study outcomes are collected using modified OSDI questionnaire answered by patients before surgery, after surgery and 7 days after surgery. These outcomes includes the frequency and severity of: * Symptoms: Blurred Vision, Eye Pain, Watery Eyes, Itchiness, Grittiness, Sensitivity to Light * Impact on daily life activities: Discomfort when Reading, Discomfort when Watching TV, Discomfort when Using Computer, Discomfort when Driving at Night, Discomfort when Being Outdoors, Discomfort when Being in Air-Conditioned Areas Frequency: Never, Some of the time, Most of the time, All of the time Severity: None, Mild, Moderate, Severe
Time frame: From enrollment to 7 days after surgery
Frequency and Severity of Sensitivity to Light symptom
All study outcomes are collected using modified OSDI questionnaire answered by patients before surgery, after surgery and 7 days after surgery. These outcomes includes the frequency and severity of: * Symptoms: Blurred Vision, Eye Pain, Watery Eyes, Itchiness, Grittiness, Sensitivity to Light * Impact on daily life activities: Discomfort when Reading, Discomfort when Watching TV, Discomfort when Using Computer, Discomfort when Driving at Night, Discomfort when Being Outdoors, Discomfort when Being in Air-Conditioned Areas Frequency: Never, Some of the time, Most of the time, All of the time Severity: None, Mild, Moderate, Severe
Time frame: From enrollment to 7 days after surgery
Frequency and Severity of Discomfort when Reading
All study outcomes are collected using modified OSDI questionnaire answered by patients before surgery, after surgery and 7 days after surgery. These outcomes includes the frequency and severity of: * Symptoms: Blurred Vision, Eye Pain, Watery Eyes, Itchiness, Grittiness, Sensitivity to Light * Impact on daily life activities: Discomfort when Reading, Discomfort when Watching TV, Discomfort when Using Computer, Discomfort when Driving at Night, Discomfort when Being Outdoors, Discomfort when Being in Air-Conditioned Areas Frequency: Never, Some of the time, Most of the time, All of the time Severity: None, Mild, Moderate, Severe
Time frame: From enrollment to 7 days after surgery
Frequency and Severity of Discomfort when Watching TV
All study outcomes are collected using modified OSDI questionnaire answered by patients before surgery, after surgery and 7 days after surgery. These outcomes includes the frequency and severity of: * Symptoms: Blurred Vision, Eye Pain, Watery Eyes, Itchiness, Grittiness, Sensitivity to Light * Impact on daily life activities: Discomfort when Reading, Discomfort when Watching TV, Discomfort when Using Computer, Discomfort when Driving at Night, Discomfort when Being Outdoors, Discomfort when Being in Air-Conditioned Areas Frequency: Never, Some of the time, Most of the time, All of the time Severity: None, Mild, Moderate, Severe
Time frame: From enrollment to 7 days after surgery
Frequency and Severity of Discomfort when Using Computer
All study outcomes are collected using modified OSDI questionnaire answered by patients before surgery, after surgery and 7 days after surgery. These outcomes includes the frequency and severity of: * Symptoms: Blurred Vision, Eye Pain, Watery Eyes, Itchiness, Grittiness, Sensitivity to Light * Impact on daily life activities: Discomfort when Reading, Discomfort when Watching TV, Discomfort when Using Computer, Discomfort when Driving at Night, Discomfort when Being Outdoors, Discomfort when Being in Air-Conditioned Areas Frequency: Never, Some of the time, Most of the time, All of the time Severity: None, Mild, Moderate, Severe
Time frame: From enrollment to 7 days after surgery
Frequency and Severity of Discomfort when Driving at Night
All study outcomes are collected using modified OSDI questionnaire answered by patients before surgery, after surgery and 7 days after surgery. These outcomes includes the frequency and severity of: * Symptoms: Blurred Vision, Eye Pain, Watery Eyes, Itchiness, Grittiness, Sensitivity to Light * Impact on daily life activities: Discomfort when Reading, Discomfort when Watching TV, Discomfort when Using Computer, Discomfort when Driving at Night, Discomfort when Being Outdoors, Discomfort when Being in Air-Conditioned Areas Frequency: Never, Some of the time, Most of the time, All of the time Severity: None, Mild, Moderate, Severe
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Time frame: From enrollment to 7 days after surgery
Frequency and Severity of Discomfort when Being Outdoors
All study outcomes are collected using modified OSDI questionnaire answered by patients before surgery, after surgery and 7 days after surgery. These outcomes includes the frequency and severity of: * Symptoms: Blurred Vision, Eye Pain, Watery Eyes, Itchiness, Grittiness, Sensitivity to Light * Impact on daily life activities: Discomfort when Reading, Discomfort when Watching TV, Discomfort when Using Computer, Discomfort when Driving at Night, Discomfort when Being Outdoors, Discomfort when Being in Air-Conditioned Areas Frequency: Never, Some of the time, Most of the time, All of the time Severity: None, Mild, Moderate, Severe
Time frame: From enrollment to 7 days after surgery
Frequency and Severity of Discomfort when Being in Air-Conditioned Areas
All study outcomes are collected using modified OSDI questionnaire answered by patients before surgery, after surgery and 7 days after surgery. These outcomes includes the frequency and severity of: * Symptoms: Blurred Vision, Eye Pain, Watery Eyes, Itchiness, Grittiness, Sensitivity to Light * Impact on daily life activities: Discomfort when Reading, Discomfort when Watching TV, Discomfort when Using Computer, Discomfort when Driving at Night, Discomfort when Being Outdoors, Discomfort when Being in Air-Conditioned Areas Frequency: Never, Some of the time, Most of the time, All of the time Severity: None, Mild, Moderate, Severe
Time frame: From enrollment to 7 days after surgery