Oncologic Outcomes of Minimal Access Nipple-sparing Mastectomy Compared With Conventional Approach in Breast Cancer

Changhua Christian Hospital1,129 enrolled

Overview

In this study the investigators investigate the oncological outcomes of minimal access nipple sparing mastectomy compared with conventional nipple sparing mastectomy for the treatment of breast cancer

A retrospective analysis of a prospectively collected database was conducted from single institute to compare the oncologic outcomes of MA-NSM versus C-NSM. The clinical results and oncologic outcome (margin involved rate, local recurrence and overall survival) were compared between groups. To prevent bias, a case control approach was conducted with propensity score matching (PSM) method.

Study Type

OBSERVATIONAL

Enrollment

1,129

Conditions

Breast Cancer

Eligibility

Sex: FEMALE

Medical Language ↔ Plain English

Inclusion Criteria: * primary operable breast cancer and had undergone NSM Exclusion Criteria: * had metastatic disease, non-malignant breast disease cases, bilateral breast cancer cases, recurrent breast cancer as well as male breast cancer cases and patients who did not undergo NSM

Outcomes

Primary Outcomes

local recurrence

Time frame: 10 years

distant metastasis

Time frame: 10 years

disease free survival

Time frame: 10 years

overall survival

Time frame: 10 years

Secondary Outcomes

operative duration

Time frame: during surgery

intra-operative blood loss

Time frame: during surgery

post-operative complications

Time frame: 30 days post-operatively

Data from ClinicalTrials.gov

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