Patients in intensive care often develop acquired muscle weakness (ICUAW or Intensive Care Unit Acquired Weakness) due to immobilization and muscle atrophy. Early mobilization can help reduce weakness and improve functional recovery, but practices vary. Muscle strength assessment, particularly using the MRC (Medical Research Council) score, is crucial, though it has precision limitations. Additional methods, such as manual dynamometry and functional scales, are needed to better track muscle recovery. The quadriceps, important for function, requires early evaluation, but there is a lack of specific data in intensive care to predict medium-term functional recovery.
Study Type
OBSERVATIONAL
Enrollment
100
Patients will undergo non-invasive assessment of quadriceps muscle strength using manual dynamometry and 3D ultrasound. These assessments will be conducted regularly during their ICU stay to evaluate early recovery. The intervention is part of routine patient care and does not involve additional treatments or procedures.
Nantes University Hospital
Nantes, Loire Atlantique, France
Describe the evolution of quadriceps muscle recovery using manual dynamometry in patients under invasive mechanical ventilation in the ICU.
This study aims to describe the evolution of quadriceps muscle recovery in ICU patients under invasive mechanical ventilation, using manual dynamometry as a measurement tool. The recovery will be assessed periodically throughout the ICU stay to evaluate early muscle strength recovery.
Time frame: 3 months
Description of the evolution of the recovery of the rectus femoris muscle using 3D ultrasound in ICU patients treated with invasive mechanical ventilation.
Change in the volume of the rectus femoris muscle measured by 3D ultrasound.
Time frame: 3 months after ICU discharge
Estimate the average value of the FMQ
Measure the FMQ (Quadriceps Muscle Strength ) at multiple key time points to estimate recovery and muscle strength progression.
Time frame: From inclusion to 3 months post-ICU discharge
To study the correlation between FMQ values and other muscular and functional scores on the same day.
Correlate FMQ with other muscular and functional scores
Time frame: From inclusion to 3 months post-ICU discharge
Study the differences in muscle strength between right and left FMQ values on the same day
Compare right and left side FMQ measurements to assess potential asymmetries.
Time frame: From inclusion to 3 months post-ICU discharge
Study the correlation between FMQ at inclusion and the time until extubation, when the patient was still intubated at inclusion
Investigate if FMQ at inclusion can predict extubation time in intubated patients.
Time frame: From inclusion to the day of extubation, an average of 7 days
Study the correlation between FMQ at inclusion and the ability to achieve verticalization for patients who could stand before ICU discharge
Examine if FMQ at inclusion is predictive of the ability to achieve verticalization during the ICU stay.
Time frame: From inclusion to ICU discharge, an average of 10 days
Study the correlation between FMQ at inclusion and the ability to take the first steps for patients who were able to walk before ICU discharge
Assess whether FMQ at inclusion predicts the ability to take first steps during the ICU stay.
Time frame: From inclusion to ICU discharge, an average of 10 days
Search for an association (survival model) between FMQ (Nm/kg) measured on the day of inclusion and the time (in days) between inclusion and the first steps taken successfully.
Study the presence of a link between FMQ (obtained on the day when the patient discharge criteria) and VFMQ (obtained between the day of inclusion and the day the patient inclusion and the day on which the patient meets the criteria for discharge from intensive care) and the patient's functional capacity at the 3-month post-resuscitation consultation. post-resuscitation, linked to an assessment of physical activity during this period. carried out during this period.
Time frame: 3 months post-ICU discharge
Examine how FMQ and VFMQ correlate with strength and functional measures at follow-up, and how physical activity impacts recovery.
To study the presence of a link between FMQ (obtained on the day the patient meets the criteria for discharge from intensive care) / VFMQ (obtained between the day of inclusion and the day the patient meets the criteria for discharge from intensive care) and the strength measurement scores obtained during the consultation 3 months after discharge from intensive care, linked to an assessment of physical activity carried out during this period. during this period.
Time frame: 3 months post-ICU discharge
Description of the recovery of the anterior tibial muscle using 3D ultrasound in ICU patients treated with invasive mechanical ventilation.
Change in the volume of the anterior tibial muscle measured by 3D ultrasound.
Time frame: 3 months after ICU discharge
Correlation between changes in rectus femoris volume and functional recovery.
Correlation between volume changes in rectus femoris muscle and functional recovery (between ICU discharge and 3 months post-ICU discharge).
Time frame: 3 months after ICU discharge
Correlation between changes in anterior tibial muscle volume and functional recovery.
Correlation between volume changes in the anterior tibial muscle and functional recovery (between ICU discharge and 3 months post-ICU discharge).
Time frame: 3 months after ICU discharge
Correlation between changes in rectus femoris volume and muscle strength assessment tools.
Time frame: 3 months after ICU discharge
Correlation between changes in anterior tibial muscle volume and muscle strength assessment tools.
Correlation between volume changes in the anterior tibial muscle and muscle strength.
Time frame: 3 months after ICU discharge
Link between rectus femoris volume and functional recovery.
Link between rectus femoris volume and functional recovery (at ICU discharge)
Time frame: at ICU discharge, an average of 10 days
Link between rectus femoris volume and functional recovery.
Link between rectus femoris volume and functional recovery (at 3 months post-ICU discharge)
Time frame: 3 months after ICU discharge
Link between anterior tibial muscle volume and functional recovery.
Link between anterior tibial muscle volume and functional recovery (at ICU discharge)
Time frame: at ICU discharge, an average of 10 days
Link between anterior tibial muscle volume and functional recovery.
Link between anterior tibial muscle volume and functional recovery (at ICU discharge)
Time frame: 3 months after ICU discharge
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